Review Collection: Pain

309 reviews

General 148 reviews
Assessment 19 reviews
Pharmacology 139 reviews



Boland EG, Bennett MI, Allgar V, Boland JW. Cannabinoids for adult cancer-related pain: systematic review and meta-analysis. BMJ Support Palliat Care. 2020 Jan 20;bmjspcare-2019-002032. doi: 10.1136/bmjspcare-2019-002032. [Epub ahead of print]. 

Chapman EJ, Edwards Z, Boland JW, Maddocks M, Fettes L, Malia C, Mulvey MR, Bennett MI. Practice review: Evidence-based and effective management of pain in patients with advanced cancer. Palliat Med. 2020 Jan 24;269216319896955. doi: 10.1177/0269216319896955. [Epub ahead of print].

Chi NC, Barani E, Fu YK, Nakad L, Gilbertson-White S, Herr K, Saeidzadeh S. Interventions to Support Family Caregivers in Pain Management: A Systematic Review. J Pain Symptom Manage. 2020 Apr 24:S0885-3924(20)30210-4. doi: 10.1016/j.jpainsymman.2020.04.014. Epub ahead of print.

Vancampfort D, Solmi M, Firth J, Vandenbulcke M, Stubbs B. The Impact of Pharmacologic and Nonpharmacologic Interventions to Improve Physical Health Outcomes in People With Dementia: A Meta-Review of Meta-Analyses of Randomized Controlled Trials. J Am Med Dir Assoc. 2020 Feb 18:S1525-8610(20)30035-9. doi: 10.1016/j.jamda.2020.01.010. Epub ahead of print.

Warth M, Zöller J, Köhler F, Aguilar-Raab C, Kessler J, Ditzen B. Psychosocial Interventions for Pain Management in Advanced Cancer Patients: a Systematic Review and Meta-analysis. Curr Oncol Rep. 2020 Jan 21;22(1):3. doi: 10.1007/s11912-020-0870-7.

Yang Y, Wen J, Hong J. The Effects of Auricular Therapy for Cancer Pain: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2020 May 25;2020:1618767. doi: 10.1155/2020/1618767.

You E. Nontraditional and Home-Based Self-management Interventions in Cancer Patients With Pain: A Mixed-Method Systematic Review. Holist Nurs Pract. 2020 May/Jun;34(3):138-149. doi: 10.1097/HNP.0000000000000380.

Zheng C, Chen X, Weng L, Guo L, Xu H, Lin M, Xue Y, Lin X, Yang A, Yu L, Xue Z, Yang J. Benefits of Mobile Apps for Cancer Pain Management: Systematic Review. JMIR Mhealth Uhealth. 2020 Jan 23;8(1):e17055. doi: 10.2196/17055.

Zhou J, Wang Y, Jiang G. Oxycodone versus morphine for cancer pain titration: A systematic review and pharmacoeconomic evaluation. PLoS One. 2020 Apr 17;15(4):e0231763. doi: 10.1371/journal.pone.0231763.


Brown D, Watson M, Schloss J. Pharmacological evidence of medicinal cannabis in oncology: a systematic review. Support Care Cancer. 2019 May 6. doi: 10.1007/s00520-019-04774-5. [Epub ahead of print]

Coronado RA, Albers HE, Allen JL, Clarke RG, Estrada VA, Simon CB, Galloway RV, Fisher SR. Pain-Reducing Effects of Physical Therapist-Delivered Interventions: A Systematic Review of Randomized Trials Among Older Adults With Dementia. J Geriatr Phys Ther. 2019 Apr 15. doi: 10.1519/JPT.0000000000000235. [Epub ahead of print]

Dillane I, Doody O. Nursing people with intellectual disability and dementia experiencing pain: An integrative review. J Clin Nurs. 2019 Feb 20. doi: 10.1111/jocn.14834. [Epub ahead of print]

Durán-Crane A, Laserna A, López-Olivo MA, Cuenca JA, Díaz DP, Cardenas YR, Urso C, O'Connell K, Azimpoor K, Fowler C, Price KJ, Sprung CL, Nates JL. Clinical Practice Guidelines and Consensus Statements About Pain Management in Critically Ill End-of-Life Patients: A Systematic Review. Crit Care Med. 2019 Sep 12. doi: 10.1097/CCM.0000000000003975. [Epub ahead of print]

Edwards Z, Ziegler L, Craigs C, Blenkinsopp A, Bennett MI. Pharmacist educational interventions for cancer pain management: a systematic review and meta-analysis. Int J Pharm Pract. 2019 Feb 1. doi: 10.1111/ijpp.12516. [Epub ahead of print]

Gao Y, Wei Y, Yang W, Jiang L, Li X, Ding J, Ding G. The Effectiveness of Music Therapy for Terminally Ill Patients: A Meta-Analysis and Systematic Review. J Pain Symptom Manage. 2019 Feb;57(2):319-329. doi: 10.1016/j.jpainsymman.2018.10.504. Epub 2018 Oct 30.

Knopp-Sihota JA, Dirk KL, Rachor GS. Factors Associated With Pain Assessment for Nursing Home Residents: A Systematic Review and Meta-Synthesis. J Am Med Dir Assoc. 2019 Mar 22. pii: S1525-8610(19)30190-2. doi: 10.1016/j.jamda.2019.01.156. [Epub ahead of print]

Lewthwaite H, Williams G, Baldock KL, Williams MT. Systematic Review of Pain in Clinical Practice Guidelines for Management of COPD: A Case for Including Chronic Pain? Healthcare (Basel). 2019 Jan 22;7(1). pii: E15. doi: 10.3390/healthcare7010015.

Livergant J, Howard M, Klein J. Barriers to Referral for Palliative Radiotherapy by Physicians: A Systematic Review. Clin Oncol (R Coll Radiol). 2019 Jan;31(1):e75-e84. doi: 10.1016/j.clon.2018.09.009. Epub 2018 Oct 21.

Millard SK, de Knegt NC. Cancer Pain in People With Intellectual Disabilities: Systematic Review and Survey of Health Care Professionals. J Pain Symptom Manage. 2019 Jul 19. pii: S0885-3924(19)30386-0. doi: 10.1016/j.jpainsymman.2019.07.013. [Epub ahead of print]

Pu L, Moyle W, Jones C, Todorovic M. Psychosocial interventions for pain management in older adults with dementia: A systematic review of randomized controlled trials. J Adv Nurs. 2019 Aug;75(8):1608-1620. doi: 10.1111/jan.13929. Epub 2019 Jan 15.

Sande TA, Laird BJA, Fallon MT. The Management of Opioid-Induced Nausea and Vomiting in Patients with Cancer: A Systematic Review. J Palliat Med. 2019 Jan;22(1):90-97. doi: 10.1089/jpm.2018.0260. Epub 2018 Sep 21.

Sørensen AMS, Tarp S, Johannsen P, Lolk A, Bandak E, Pedersen H, Saxtrup N, Kallehauge H, Solem EJ, Christensen MB. Analgesics use and withdrawal in people with dementia - a register-based Danish study and a systematic review. Dan Med J. 2019 Dec;66(12). pii: A5578.

Yangöz ŞT, Özer Z. The effect of music intervention on patients with cancer-related pain: A systematic review and meta-analysis of randomized controlled trials. J Adv Nurs. 2019 Aug 26. doi: 10.1111/jan.14184. [Epub ahead of print]


Abahussin AA, West RM, Wong DC, Ziegler LE. PROMs for pain in adult cancer patients: a systematic review of measurement properties. Pain Pract. 2018 May 17. doi: 10.1111/papr.12711. [Epub ahead of print]

Bouya S, Balouchi A, Maleknejad A, Koochakzai M, AlKhasawneh E, Abdollahimohammad A. Cancer Pain Management Among Oncology Nurses: Knowledge, Attitude, Related Factors, and Clinical Recommendations: a Systematic Review. J Cancer Educ. 2018 Oct 12. doi: 10.1007/s13187-018-1433-6. [Epub ahead of print]

Demaneuf T, Aitken Z, Karahalios A, Leong TI, De Livera AM, Jelinek GA, Weiland TJ, Marck CH. The effectiveness of exercise interventions for pain reduction in people with multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials. Arch Phys Med Rehabil. 2018 Sep 18. pii: S0003-9993(18)31191-2. doi: 10.1016/j.apmr.2018.08.178. [Epub ahead of print]

Harrington SE, Gilchrist L, Lee J, Westlake FL, Baker A. Oncology Section EDGE Task Force on Cancer: A Systematic Review of Clinical Measures for Pain. Rehabil Oncol. 2018 Apr;36(2):83-92.

Ferrer-Mileo L, Luque Blanco AI, González-Barboteo J. Efficacy of Cryoablation to Control Cancer Pain: A Systematic Review. Pain Pract. 2018 Nov;18(8):1083-1098. doi: 10.1111/papr.12707. Epub 2018 Jun 7.

Hilfiker R, Meichtry A, Eicher M, Nilsson Balfe L, Knols RH, Verra ML, Taeymans J. Exercise and other non-pharmaceutical interventions for cancer-related fatigue in patients during or after cancer treatment: a systematic review incorporating an indirect-comparisons meta-analysis. Br J Sports Med. 2018 May;52(10):651-658. doi: 10.1136/bjsports-2016-096422. Epub 2017 May 13.

Kane CM, Mulvey MR, Wright S, Craigs C, Wright JM, Bennett MI. Opioids combined with antidepressants or antiepileptic drugs for cancer pain: Systematic review and meta-analysis. Palliat Med. 2018 Jan;32(1):276-286. doi: 10.1177/0269216317711826. Epub 2017 Jun 12.

Lu F, Dong J, Tang Y, Huang H, Liu H, Song L, Zhang K. Bilateral vs. unilateral endoscopic ultrasound-guided celiac plexus neurolysis for abdominal pain management in patients with pancreatic malignancy: a systematic review and meta-analysis. Support Care Cancer. 2018 Feb;26(2):353-359. doi: 10.1007/s00520-017-3888-0. Epub 2017 Sep 27.

Mayahara M, Wilbur J, Fogg L, Breitenstein SM. Behavioral Pain Intervention for Hospice and Palliative Care Patients: An Integrative Review. Am J Hosp Palliat Care. 2018 Sep;35(9):1245-1255. doi: 10.1177/1049909118775421. Epub 2018 May 17.

Mitchell GK, Senior HE, Johnson CE, Fallon-Ferguson J, Williams B, Monterosso L, Rhee JJ, McVey P, Grant MP, Aubin M, Nwachukwu HT, Yates PM. Systematic review of general practice end-of-life symptom control. BMJ Support Palliat Care. 2018 Jan 20. pii: bmjspcare-2017-001374. doi: 10.1136/bmjspcare-2017-001374. [Epub ahead of print]

Polastri M, Comellini V, Pacilli AMG, Nava S. Magnetic Stimulation Therapy in Patients with COPD: A Systematic Review. COPD. 2018 Mar 20:1-6. doi: 10.1080/15412555.2018.1439910. [Epub ahead of print]

Rana AQ, Qureshi AR, Siddiqui O, Sarfraz Z, Rana R, Shtilbans A. Prevalence of pain in atypical parkinsonism: a systematic review and meta-analysis. J Neurol. 2018 Sep 20. doi: 10.1007/s00415-018-9049-7. [Epub ahead of print]

Rich SE, Chow R, Raman S, Liang Zeng K, Lutz S, Lam H, Silva MF, Chow E. Update of the systematic review of palliative radiation therapy fractionation for bone metastases. Radiother Oncol. 2018 Mar;126(3):547-557. doi: 10.1016/j.radonc.2018.01.003. Epub 2018 Feb 1.

Schüchen RH, Mücke M, Marinova M, Kravchenko D, Häuser W, Radbruch L, Conrad R. Systematic review and meta-analysis on non-opioid analgesics in palliative medicine. J Cachexia Sarcopenia Muscle. 2018 Dec;9(7):1235-1254. doi: 10.1002/jcsm.12352. Epub 2018 Oct 29.

Smyth JA, Dempster M, Warwick I, Wilkinson P, McCorry NK. A Systematic Review of the Patient- and Carer-Related Factors Affecting the Experience of Pain for Advanced Cancer Patients Cared for at Home. J Pain Symptom Manage. 2018 Feb;55(2):496-507. doi: 10.1016/j.jpainsymman.2017.08.012. Epub 2017 Aug 24.

Strand LI, Gundrosen KF, Lein RK, Laekeman M, Lobbezoo F, Defrin R, Husebo BS. Body movements as pain indicators in older people with cognitive impairment: A systematic review. Eur J Pain. 2018 Nov 19. doi: 10.1002/ejp.1344. [Epub ahead of print]

Venasse M, Edwards T, Pilutti LA. Exploring Wellness Interventions in Progressive Multiple Sclerosis: an Evidence-Based Review. Curr Treat Options Neurol. 2018 Apr 10;20(5):13. doi: 10.1007/s11940-018-0497-2.


Ahmed Y, Popovic M, Wan BA, Lam M, Lam H, Ganesh V, Milakovic M, DeAngelis C, Malek L, Chow E. Does gender affect self-perceived pain in cancer patients? -A meta-analysis. Ann Palliat Med. 2017 Dec;6(Suppl 2):S177-S184. doi: 10.21037/apm.2017.08.09. Epub 2017 Sep 12.

Chow R, Hoskin P, Chan S, Mesci A, Hollenberg D, Lam H, DeAngelis C, Chow E. Efficacy of multiple fraction conventional radiation therapy for painful uncomplicated bone metastases: A systematic review. Radiother Oncol. 2017 Mar;122(3):323-331. doi: 10.1016/j.radonc.2016.12.031. Epub 2017 Jan 12.

Holmes MM, Lewith G, Newell D, Field J, Bishop FL. The impact of patient-reported outcome measures in clinical practice for pain: a systematic review. Qual Life Res. 2017 Feb;26(2):245-257. Epub 2016 Nov 4.

Zylla D, Steele G, Gupta P. A systematic review of the impact of pain on overall survival in patients with cancer. Support Care Cancer. 2017 May;25(5):1687-1698. Epub 2017 Feb 11.


Chi NC, Demiris G. Family caregivers' pain management in end-of-life care: A systematic review. Am J Hosp Palliat Care. 2017 Jun;34(5):470-485. Epub 2016 Mar 14.

Husebo BS, Achterberg W, Flo E. Identifying and Managing Pain in People with Alzheimer's Disease and Other Types of Dementia: A Systematic Review. CNS Drugs. 2016 Jun;30(6):481-97.

Lee JH. The Effects of Music on Pain: A Meta-Analysis. J Music Ther. 2016 Winter;53(4):430-477. Epub 2016 Oct 19.

Mercadante S, Klepstad P, Paula Kurita G, Sjøgren P, Pigni A, Caraceni A. Minimally invasive procedures for the management of vertebral bone pain due to cancer: The EAPC recommendations. Acta Oncol. 2016;55(2):129-33.Epub 2015 Sep 15.

Roberto A, Deandrea S, Greco MT, Corli O, Negri E, Pizzuto M, Ruggeri F. Prevalence of Neuropathic Pain in Cancer Patients: Pooled Estimates From a Systematic Review of Published Literature and Results From a Survey Conducted in 50 Italian Palliative Care Centers. J Pain Symptom Manage. 2016 Jun;51(6):1091-1102.e4. Epub 2016 Mar 25.

Santos Salas A, Fuentes Contreras J, Armijo-Olivo S, Saltaji H, Watanabe S, Chambers T, Walter L, Cummings GG. Non-pharmacological cancer pain interventions in populations with social disparities: a systematic review and meta-analysis. Support Care Cancer. 2016 Feb;24(2):985-1000. Epub 2015 Nov 10.

van den Beuken-van Everdingen MH, Hochstenbach LM, Joosten EA, Tjan-Heijnen VC, Janssen DJ. Update on Prevalence of Pain in Patients With Cancer: Systematic Review and Meta-Analysis. J Pain Symptom Manage. 2016 Jun;51(6):1070-1090.e9. Epub 2016 Apr 23.


Adam R, Bond C, Murchie P. Educational interventions for cancer pain. A systematic review of systematic reviews with nested narrative review of randomized controlled trials. Patient Educ Couns. 2015 Mar;98(3):269-82 Epub 2014 Nov 18.

Allsop MJ, Taylor S, Mulvey MR, Bennett MI, Bewick BM. Information and communication technology for managing pain in palliative care: a review of the literature. BMJ Support Palliat Care. 2015 Dec;5(5):481-9. Epub 2014 Mar 11.

Klepstad P, Kurita GP, Mercadante S, Sjøgren P. Evidence of peripheral nerve blocks for cancer-related pain: a systematic review. Minerva Anestesiol. 2015 Jul;81(7):789-93. Epub 2014 Nov 11.

Mercadante S, Klepstad P, Kurita GP, Sjøgren P, Giarratano A; European Palliative Care Research Collaborative (EPCRC). Sympathetic blocks for visceral cancer pain management: A systematic review and EAPC recommendations. Crit Rev Oncol Hematol. 2015 Dec;96(3):577-83. doi: 10.1016/j.critrevonc.2015.07.014. Epub 2015 Aug 1.


Deandrea S, Corli O, Consonni D, Villani W, Greco MT, Apolone G. Prevalence of breakthrough cancer pain: a systematic review and a pooled analysis of published literature. J Pain Symptom Manage. 2014 Jan;47(1):57-76.Epub 2013 Jun 21.

Drageset J, Corbett A, Selbaek G, Husebo BS. Cancer-related pain and symptoms among nursing home residents: a systematic review. J Pain Symptom Manage. 2014 Oct;48(4):699-710.e1. Epub 2014 Apr 3.

France BD, Lewis RA, Sharma ML, Poolman M. Cordotomy in mesothelioma-related pain: a systematic review. BMJ Support Palliat Care. 2014 Mar;4(1):19-29. Epub 2013 Sep 18.

Good P, Afsharimani B, Movva R, Haywood A, Khan S, Hardy J. Therapeutic challenges in cancer pain management: a systematic review of methadone. J Pain Palliat Care Pharmacother. 2014 Sep;28(3):197-205. Epub 2014 Aug 7.

Hökkä M, Kaakinen P, Pölkki T. A systematic review: non-pharmacological interventions in treating pain in patients with advanced cancer. J Adv Nurs. 2014 Sep;70(9):1954-69.

Martinez KA, Aslakson RA, Wilson RF, Apostol CC, Fawole OA, Lau BD, Vollenweider D, Bass EB, Dy SM. A systematic review of health care interventions for pain in patients with advanced cancer. Am J Hosp Palliat Care. 2014 Feb;31(1):79-86. Epub 2013 Feb 12.

Seixas D, Foley P, Palace J, Lima D, Ramos I, Tracey I. Pain in multiple sclerosis: a systematic review of neuroimaging studies. Neuroimage Clin. 2014 Jul 5;5:322-31.

Wittenberg-Lyles E, Parker Oliver D, Demiris G, Swarz J, Rendo M. YouTube as a tool for pain management with informal caregivers of cancer patients: a systematic review. J Pain Symptom Manage. 2014 Dec;48(6):1200-10. doi: 10.1016/j.jpainsymman.2014.02.015. Epub 2014 Apr 30.

Zeppetella G, Davies A, Eijgelshoven I, Jansen JP. A network meta-analysis of the efficacy of opioid analgesics for the management of breakthrough cancer pain episodes. J Pain Symptom Manage. 2014 Apr;47(4):772-785.e5.


Abdulla A, Adams N, Bone M, Elliott AM, Gaffin J, Jones D, Knaggs R, Martin D, Sampson L, Schofield P. Guidance on the management of pain in older people. Age Ageing. 2013 Mar;42 Suppl 1:i1-57.

de Knegt NC, Pieper MJ, Lobbezoo F, Schuengel C, Evenhuis HM, Passchier J, Scherder EJ. Behavioral pain indicators in people with intellectual disabilities: a systematic review. J Pain. 2013 Sep;14(9):885-96. Epub 2013 Jul 3.

Jho HJ, Myung SK, Chang YJ, Kim DH, Ko DH. Efficacy of pain education in cancer patients: A meta-analysis of randomized controlled trials. Support Care Cancer. 2013 Jul;21(7):1963-71. doi: 10.1007/s00520-013-1756-0. Epub 2013 Feb 21.

Marie N, Luckett T, Davidson PM, Lovell M, Lal S. Optimal patient education for cancer pain: a systematic review and theory-based meta-analysis. Support Care Cancer. 2013 Dec;21(12):3529-37. Epub 2013 Oct 2.

Rork JF, Berde CB, Goldstein RD. Regional anesthesia approaches to pain management in pediatric palliative care: a review of current knowledge. J Pain Symptom Manage. 2013 Dec;46(6):859-73. Epub 2013 Mar 29.

Saylor PJ, Armstrong AJ, Fizazi K, Freedland S, Saad F, Smith MR, Tombal B, Pienta K. New and emerging therapies for bone metastases in genitourinary cancers. Eur Urol. 2013 Feb;63(2):309-20.Epub 2012 Nov 23


Bennett MI, Rayment C, Hjermstad M, Aass N, Caraceni A, Kaasa S. Prevalence and aetiology of neuropathic pain in cancer patients: a systematic review. Pain. 2012 Feb;153(2):359-65. Epub 2011 Nov 23.

Chen CH, Tang ST, Chen CH. Meta-analysis of cultural differences in Western and Asian patient-perceived barriers to managing cancer pain. Palliat Med. 2012 Apr;26(3):206-21. Epub 2011 Apr 7.

Choi TY, Lee MS, Kim TH, Zaslawski C, Ernst E. Acupuncture for the treatment of cancer pain: a systematic review of randomised clinical trials. Support Care Cancer. 2012 Jun;20(6):1147-58. Epub 2012 Mar 25.

Dy SM, Aslakson R, Wilson RF, Fawole OA, Lau BD, Martinez KA, Vollenweider D, Apostol C, Bass EB. Improving health care and palliative care for advanced and serious illness. Agency for Healthcare Research and Quality. Rockville, MD, October 2012. [No abstract available]

Jandhyala R, Fullarton J. Various formulations of oral transmucosal fentanyl for breakthrough cancer pain: an indirect mixed treatment comparison meta-analysis. BMJ Support Palliat Care. 2012 Jun;2(2):156-62.

Koller A, Miaskowski C, De Geest S, Opitz O, Spichiger E. A systematic evaluation of content, structure, and efficacy of interventions to improve patients' self-management of cancer pain. J Pain Symptom Manage. 2012 Aug;44(2):264-84.

Posadzki P, Lewandowski W, Terry R, Ernst E, Stearns. A Guided imagery for non-musculoskeletal pain: a systematic review of randomized clinical trials. J Pain Symptom Manage. 2012 Jul;44(1):95-104. pub 2012 Jun 5.

Sheinfeld Gorin S, Krebs P, Badr H, Janke EA, Jim HS, Spring B, Mohr DC, Berendsen MA, Jacobsen PB. Meta-analysis of psychosocial interventions to reduce pain in patients with cancer. J Clin Oncol. 2012 Feb 10;30(5):539-47. Epub 2012 Jan 17.


Bender JL, Radhakrishnan A, Diorio C, Englesakis M, Jadad AR. Can pain be managed through the Internet? A systematic review of randomized controlled trials. Pain. 2011 Aug;152(8):1740-50. Epub 2011 May 11.

Bennett MI, Hughes N, Johnson MI. Methodological quality in randomised controlled trials of transcutaneous electric nerve stimulation for pain: low fidelity may explain negative findings. Pain. 2011 Jun;152(6):1226-32. Epub 2011 Mar 23.

Cummings GG, Olivo SA, Biondo PD, Stiles CR, Yurtseven O, Fainsinger RL, Hagen NA. Effectiveness of knowledge translation interventions to improve cancer pain management. J Pain Symptom Manage. 2011 May;41(5):915-39. Epub 2011 Mar 12

Chew C, Craig L, Edwards R, Moss J, O'Dwyer PJ. Safety and efficacy of percutaneous vertebroplasty in malignancy: a systematic review. Clin Radiol. 2011 Jan;66(1):63-72. Epub 2010 Nov 16.

Dalacorte RR, Rigo JC, Dalacorte A. Pain management in the elderly at the end of life. N Am J Med Sci. 2011 Aug;3(8):348-54.

Falkensteiner M, Mantovan F, Müller I, Them C. The use of massage therapy for reducing pain, anxiety, and depression in oncological palliative care patients: a narrative review of the literature. ISRN Nurs. 2011;2011:929868. Epub 2011 Aug 23.

Kirby M, Hirst C, Crawford ED. Characterising the castration-resistant prostate cancer population: a systematic review. Int J Clin Pract. 2011 Nov;65(11):1180-92.

Kumar S. Reporting characteristics of cancer pain: A systematic review and quantitative analysis of research publications in palliative care journals. Indian Journal of Palliative Care. 2011 Jan;17(1):57.

Meeker MA, Finnell D, Othman AK. Family caregivers and cancer pain management: a review. J Fam Nurs. 2011 Feb;17(1):29-60.

Paley CA, Tashani OA, Bagnall AM, Johnson MI. A Cochrane systematic review of acupuncture for cancer pain in adults. BMJ Support Palliat Care. 2011 Jun;1(1):51-5.

Stone P, Minton O. European Palliative Care Research collaborative pain guidelines. Central side-effects management: what is the evidence to support best practice in the management of sedation, cognitive impairment and myoclonus? Palliat Med. 2011 Jul 1;25(5):431-41.


Dy SM. Evidence-based approaches to pain in advanced cancer. Cancer J. 2010 Sep-Oct;16(5):500-6.

Epstein JB, Hong C, Logan RM, Barasch A, Gordon SM, Oberle-Edwards L, McGuire D, Napenas JJ, Elting LS, Spijkervet FK, Brennan MT. A systematic review of orofacial pain in patients receiving cancer therapy. Support Care Cancer. 2010 Aug;18(8):1023-31. Epub 2010 Jun 11.

Green E, Zwaal C, Beals C, Fitzgerald B, Harle I, Jones J, Tsui J, Volpe J, Yoshimoto D, Wiernikowski J. Cancer-related pain management: a report of evidence-based recommendations to guide practice. Clin J Pain. 2010 Jul-Aug;26(6):449-62.

Hopkins Hollis AS. Acupuncture as a treatment modality for the management of cancer pain: the state of the science. Oncol Nurs Forum. 2010 Sep 1;37(5):E344-8.

Myers J, Chan V, Jarvis V, Walker-Dilks C. Intraspinal techniques for pain management in cancer patients: a systematic review. Support Care Cancer. 2010 Feb;18(2):137-49.

Shavers VL, Bakos A, Sheppard VB. Race, ethnicity, and pain among the U.S. adult population. J Health Care Poor Underserved. 2010 Feb;21(1):177-220.

Stiles CR, Biondo PD, Cummings G, Hagen NA. Clinical trials focusing on cancer pain educational interventions: core components to include during planning and reporting. J Pain Symptom Manage. 2010 Aug;40(2):301-8. Epub 2010 Jun 11.


Anderson KO, Green CR, Payne R. Racial and ethnic disparities in pain: causes and consequences of unequal care. J Pain. 2009 Dec;10(12):1187-204.

Aprili D, Bandschapp O, Rochlitz C, Urwyler A, Ruppen W. Serious complications associated with external intrathecal catheters used in cancer pain patients: a systematic review and meta-analysis. Anesthesiology. 2009 Dec;111(6):1346-55.

Bennett MI, Bagnall AM, José Closs S. How effective are patient-based educational interventions in the management of cancer pain? Systematic review and meta-analysis. Pain. 2009 Jun;143(3):192-9. Epub 2009 Mar 12.

Davies AN, Dickman A, Reid C, Stevens AM, Zeppetella G; Science Committee of the Association for Palliative Medicine of Great Britain and Ireland. The management of cancer-related breakthrough pain: recommendations of a task group of the Science Committee of the Association for Palliative Medicine of Great Britain and Ireland. Eur J Pain. 2009 Apr;13(4):331-8. Epub 2008 Aug 15.

Herman AD, Johnson TM 2nd, Ritchie CS, Parmelee PA. Pain management interventions in the nursing home: a structured review of the literature. J Am Geriatr Soc. 2009 Jul;57(7):1258-67. Epub 2009 Jun 3.

Jacobsen R, Møldrup C, Christrup L, Sjøgren P. Patient-related barriers to cancer pain management: a systematic exploratory review. Scand J Caring Sci. 2009 Mar;23(1):190-208. Epub 2008 Sep 10.

Kurita GP, Lundorff L, Pimenta CA, Sjøgren P. The cognitive effects of opioids in cancer: a systematic review. Support Care Cancer. 2009 Jan;17(1):11-21. Epub 2008 Sep 2.

Laird BJ, Boyd AC, Colvin LA, Fallon MT. Are cancer pain and depression interdependent? a systematic review. Psychooncology. 2009 May;18(5):459-64.

Lorenz KA, Dy SM, Naeim A, Walling AM, Sanati H, Smith P, Shanman R, Roth CP, Asch SM. Quality measures for supportive cancer care: the Cancer Quality-ASSIST Project. J Pain Symptom Manage. 2009 Jun;37(6):943-64. Epub 2009 Apr 8.

McAuliffe L, Nay R, O'Donnell M, Fetherstonhaugh D. Pain assessment in older people with dementia: literature review. J Adv Nurs. 2009 Jan;65(1):2-10. Epub 2008 Nov 11.

Oldenmenger WH, Sillevis Smitt PA, van Dooren S, Stoter G, van der Rijt CC. A systematic review on barriers hindering adequate cancer pain management and interventions to reduce them: a critical appraisal. Eur J Cancer. 2009 May;45(8):1370-80. Epub 2009 Feb 7.

Robb K, Oxberry SG, Bennett MI, Johnson MI, Simpson KH, Searle RD. A cochrane systematic review of transcutaneous electrical nerve stimulation for cancer pain. J Pain Symptom Manage. 2009 Apr;37(4):746-53. Epub 2008 Sep 14.


Brink-Huis A, van Achterberg T, Schoonhoven L. Pain management: a review of organisation models with integrated processes for the management of pain in adult cancer patients. J Clin Nurs. 2008 Aug;17(15):1986-2000.

Carlson C. Development and testing of four instruments to assess prior conditions that influence nurses' adoption of evidence-based pain management practices. J Adv Nurs. 2008 Dec;64(6):632-43.

Courtenay M, Carey N. The impact and effectiveness of nurse-led care in the management of acute and chronic pain: a review of the literature. J Clin Nurs. 2008 Aug;17(15):2001-13.

Deandrea S, Montanari M, Moja L, Apolone G. Prevalence of undertreatment in cancer pain. a review of published literature. Ann Oncol. 2008 Dec;19(12):1985-91. Epub 2008 Jul 15.

Jackson E, Kelley M, McNeil P, Meyer E, Schlegel L, Eaton M. Does therapeutic touch help reduce pain and anxiety in patients with cancer? Clin J Oncol Nurs. 2008 Feb;12(1):113-20.

Liu Y, Fawcett TN. The role of massage therapy in the relief of cancer pain. Nurs Stand. 2008 Jan 30-Feb 5;22(21):35-40.

Lorenz KA, Lynn J, Dy SM, Shugarman LR, Wilkinson A, Mularski RA, Morton SC, Hughes RG, Hilton LK, Maglione M, Rhodes SL, Rolon C, Sun VC, Shekelle PG. Evidence for improving palliative care at the end of life: a systematic review. Ann Intern Med. 2008 Jan 15;148(2):147-59.

Pittler MH, Ernst E. Complementary therapies for neuropathic and neuralgic pain: systematic review. Clin J Pain. 2008 Oct;24(8):731-3.

Qaseem A, Snow V, Shekelle P, Casey DE, Jr., Cross JT, Jr., Owens DK, Clinical Efficacy Assessment Subcommittee of the American College of Physicians, Dallas P, Dolan NC, Forciea MA, Halasyamani L, Hopkins RH Jr, Shekelle P. Evidence-based interventions to improve the palliative care of pain, dyspnea, and depression at the end of life: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2008 Jan 15;148(2):141-6.

Robb KA, Bennett MI, Johnson MI, Simpson KJ, Oxberry SG. Transcutaneous electric nerve stimulation (TENS) for cancer pain in adults. Cochrane Database Syst Rev. 2008 Jul 16;(3):CD006276. [Updated 2012]

Weschules DJ, Bain KT, Richeimer S. Actual and potential drug interactions associated with methadone. Pain Med. 2008 Apr;9(3):315-44.


Chow E, Harris K, Fan G, Tsao M, Sze WM. Palliative radiotherapy trials for bone metastases: a systematic review. J Clin Oncol. 2007 Apr 10;25(11):1423-36.

Cole JC, Dubois D, Kosinski M. Use of patient-reported sleep measures in clinical trials of pain treatment: a literature review and synthesis of current sleep measures and a conceptual model of sleep disturbance in pain. Clin Ther. 2007;29 Suppl:2580-8.

Etzioni S, Chodosh J, Ferrell BA, MacLean CH. Quality indicators for pain management in vulnerable elders. J Am Geriatr Soc. 2007 Oct;55 Suppl 2:S403-8.

Gagliese L, Gauthier LR, Rodin G. Cancer pain and depression: a systematic review of age-related patterns. Pain Res Manag. 2007 Autumn;12(3):205-11.

Goldberg GR, Morrison RS. Pain management in hospitalized cancer patients: a systematic review. J Clin Oncol. 2007 May 1;25(13):1792-801.

Jacobsen R, Sjogren P, Moldrup C, Christrup L. Physician-related barriers to cancer pain management with opioid analgesics: a systematic review. J Opioid Manag. 2007 Jul-Aug;3(4):207-14.

Richards T, Johnson J, Sparks A, Emerson H. The effect of music therapy on patients' perception and manifestation of pain, anxiety, and patient satisfaction. Medsurg Nurs. 2007 Feb;16(1):7-14.

van den Beuken-van Everdingen MH, de Rijke JM, Kessels AG, Schouten HC, van Kleef M, Patijn J. Prevalence of pain in patients with cancer: a systematic review of the past 40 years. Ann Oncol. 2007 Sep;18(9):1437-49. Epub 2007 Mar 12.

Visovsky C, Collins M, Abbott L, Aschenbrenner J, Hart C. Putting evidence into practice: evidence-based interventions for chemotherapy-induced peripheral neuropathy. Clin J Oncol Nurs. 2007 Dec;11(6):901-13.


Azevedo K, Ferreira SL, Kinmura M, Teixeira M. The WHO analgesic ladder for cancer pain control, twenty years of use. how much pain relief does one get from it? Support Care Cancer. 2006 Nov;14(11):1086-93. Epub 2006 Jun 8.

Bardia A, Barton DL, Prokop LJ, Bauer BA, Moynihan TJ. Efficacy of complementary and alternative medicine therapies in relieving cancer pain: a systematic review. J Clin Oncol. 2006 Dec 1;24(34):5457-64.

Cepeda MS, Carr DB, Lau J, Alvarez H. Music for pain relief. Cochrane Database Syst Rev. 2006 Apr 19;(2):CD004843.

Cintron A, Morrison RS. Pain and ethnicity in the United States: a systematic review. J Palliat Med. 2006 Dec;9(6):1454-73.

Irajpour A. Interprofessional education: a facilitator to enhance pain management? J Interprof Care. 2006 Dec;20(6):675-8.

Lynch ME, Watson CP. The pharmacotherapy of chronic pain: a review. Pain Res Manag. 2006 Spring;11(1):11-38.

Richardson J, Smith JE, McCall G, Pilkington K. Hypnosis for procedure-related pain and distress in pediatric cancer patients: a systematic review of effectiveness and methodology related to hypnosis interventions. J Pain Symptom Manage. 2006;31(1):70-84.


Ballantyne JC, Carwood CM. Comparative efficacy of epidural, subarachnoid, and intracerebroventricular opioids in patients with pain due to cancer. Cochrane Database Syst Rev. 2005 Apr 20;(2):CD005178. [Withdrawn 2013]

Finnerup NB, Otto M, McQuay HJ, Jensen TS, Sindrup SH. Algorithm for neuropathic pain treatment: An evidence based proposal. Pain. 2005 Dec 5;118(3):289-305. Epub 2005 Oct 6.

Lee H, Schmidt K, Ernst E. Acupuncture for the relief of cancer-related pain--a systematic review. Eur J Pain. 2005 Aug;9(4):437-44.


Carr DB, Goudas LC, Balk EM, Bloch R, Ioannidis JP, Lau J. Evidence report on the treatment of pain in cancer patients. J Natl Cancer Inst Monogr. 2004;(32):23-31.

Patrick D, Ferketich S, Frame P, Harris J, Hendricks C, Levin B, Link MP, Lustig C, McLaughlin J, Reid LD, Turrisi AT 3rd, Unützer J, Vernon SW; National Institutes of Health State-of-the-Science Panel. National Institutes of Health state-of-the-science conference statement: symptom management in cancer: pain, depression, and fatigue, July 15-17, 2002. J Natl Cancer Inst Monogr. 2004;(32):9-16.


Devine EC. Meta-analysis of the effect of psychoeducational interventions on pain in adults with cancer. Oncol Nurs Forum. 2003 Jan-Feb;30(1):75-89.


Carr D, Goudas L, Lawrence D, Pirl W, Lau J, DeVine D, Kupelnick B, Miller K. Management of cancer symptoms: pain, depression, and fatigue. Evid Rep Technol Assess (Summ). 2002 Jul;(61):1-5.

Sze WM, Shelley M, Held I, Mason M. Palliation of metastatic bone pain: single fraction versus multifraction radiotherapy. Cochrane Database Syst Rev. 2002;(1):CD004721.

Wu JS, Bezjak A, Chow E, Kirkbride P. Primary treatment endpoint following palliative radiotherapy for painful bone metastases: need for a consensus definition? Clin Oncol (R Coll Radiol). 2002 Feb;14(1):70-7.

Zaza C, Baine N. Cancer pain and psychosocial factors: a critical review of the literature. J Pain Symptom Manage. 2002 Nov;24(5):526-42.


Allard P, Maunsell E, Labbe J, Dorval M. Educational interventions to improve cancer pain control: a systematic review. J Palliat Med. 2001 Summer;4(2):191-203.

Thomsen AB, Sorenson J, Sjogren P, Eriksen J. Economic evaluation of multidisciplinary pain management in chronic pain patients: a qualitative systematic review. J Pain Symptom Manage. 2001 Aug;22(2):688-98.


Bennett G, Serafini M, Burchiel K, Buchser E, Classen A, Deer T, Du Pen S, Ferrante FM, Hassenbusch SJ, Lou L, Maeyaert J, Penn R, Portenoy RK, Rauck R, Willis KD, Yaksh T. Evidence-based review of the literature on intrathecal delivery of pain medication. J Pain Symptom Manage. 2000 Aug;20(2):S12-36.

Pan CX, Morrison RS, Ness J, Fugh-Berman A, Leipzig RM. Complementary and alternative medicine in the management of pain, dyspnea, and nausea and vomiting near the end of life. A systematic review. J Pain Symptom Manage. 2000 Nov;20(5):374-87.


McQuay HJ, Carroll D, Moore RA. Radiotherapy for painful bone metastases: a systematic review. Clin Oncol (R Coll Radiol). 1997;9(3):150-4. Review. No abstract available.


Eisenberg E, Carr DB, Chalmers TC. Neurolytic celiac plexus block for treatment of cancer pain: a meta-analysis. Anesth Analg. 1995 Feb;80(2):290-5. (63kb pdf)

Assessment: 19 reviews


Coca SM, Abeldaño Zuñiga RA. Instruments for pain assessment in patients with advanced dementia: A systematic review of the evidence for Latin America. Palliat Support Care. 2020 Jan 10;1-7. doi: 10.1017/S147895151900107X. [Epub ahead of print].


Martland ME, Rashidi AS, Bennett MI, Fallon M, Jones C, Rolke R, Mulvey MR. The use of Quantitative Sensory Testing (QST) in cancer pain assessment: A systematic review. Eur J Pain. 2019 Dec 10. doi: 10.1002/ejp.1520. [Epub ahead of print]

Tapp D, Chenacher S, Gérard NPA, Bérubé-Mercier P, Gelinas C, Douville F, Desbiens JF. Observational Pain Assessment Instruments for Use With Nonverbal Patients at the End-of-life: A Systematic Review. J Palliat Care. 2019 Jan 13:825859718816073. doi: 10.1177/0825859718816073. [Epub ahead of print]


Geddis-Regan AR, Stewart M, Wassall RR. Orofacial Pain Assessment and Management for Patients with Dementia: A Meta-Ethnography. J Oral Rehabil. 2018 Oct 11. doi: 10.1111/joor.12732. [Epub ahead of print]


Takahashi R, Morita T, Miyashita M. Variations in Denominators and Cut-off Points of Pain Intensity in the Pain Management Index: A Methodological Systematic Review. J Pain Symptom Manage. 2017 Nov;54(5):e1-e4. doi: 10.1016/j.jpainsymman.2017.08.026. Epub 2017 Sep 1.


Luckett T, Davidson PM, Green A, Boyle F, Stubbs J, Lovell M. Assessment and management of adult cancer pain: a systematic review and synthesis of recent qualitative studies aimed at developing insights for managing barriers and optimizing facilitators within a comprehensive framework of patient care. J Pain Symptom Manage. 2013 Aug;46(2):229-53. Epub 2012 Nov 15.

Zeppetella G, Davies AN. Opioids for the management of breakthrough pain in cancer patients. Cochrane Database Syst Rev. 2013 Oct 21;10:CD004311. [Updated review]


Kurita GP, Ulrich A, Jensen TS, Werner MU, Sjøgren P. How is neuropathic cancer pain assessed in randomised controlled trials? Pain. 2012 Jan;153(1):13-7. Epub 2011 Sep 7. [No abstract available]

Ngamkham S, Vincent C, Finnegan L, Holden JE, Wang ZJ, Wilkie DJ. The McGill Pain Questionnaire as a multidimensional measure in people with cancer: an integrative review. Pain Manag Nurs. 2012 Mar;13(1):27-51. Epub 2011 May 20.

Situ Dongrong, Wang Jiang, Shao Wenlong, Zhu Zhi-hua. Assessment and treatment of cancer pain: From Western to Eastern. Ann Palliat Med. 2012; 1(1): 32-44. [no abstract]


Hjermstad MJ, Fayers PM, Haugen DF, Caraceni A, Hanks GW, Loge JH, Fainsinger R, Aass N, Kaasa S; European Palliative Care Research Collaborative (EPCRC). Studies comparing numerical rating scales, verbal rating scales, and visual analogue scales for assessment of pain intensity in adults: a systematic literature review. J Pain Symptom Manage. 2011 Jun;41(6):1073-93.

Ni Thuathail A, Welford C. Pain assessment tools for older people with cognitive impairment. Nurs Stand.2011 Oct 12-18;26(6):39-46.


Knudsen AK, Aass N, Fainsinger R, Caraceni A, Klepstad P, Jordhøy M, Hjermstad MJ, Kaasa S. Classification of pain in cancer patients--a systematic literature review. Palliat Med. 2009 Jun;23(4):295-308. Epub 2009 Mar 13.

LeBon B, Zeppetella G, Higginson IJ. Effectiveness of topical administration of opioids in palliative care: a systematic review. J Pain Symptom Manage. 2009 May;37(5):913-7. Epub 2009 Mar 24.


McAuliffe L, Nay R, O'Donnell M, Fetherstonhaugh D. Pain assessment in older people with dementia: literature review. J Adv Nurs. 2009 Jan;65(1):2-10.


Holen J, Hjermstad M, Loge J, Fayers P, Caraceni A, De Conno F, Forbes K, Fürst CJ, Radbruch L, Kaasa S. Pain assessment tools: is the content appropriate for use in palliative care? J Pain Symptom Manage. 2006 Dec;32(6):567-80.


Caraceni A, Brunelli C, Martini C, Zecca E, De Conno F. Cancer pain assessment in clinical trials. A review of the literature (1999-2002). J Pain Symptom Manage. 2005 May;29(5):507-19.

Smith M. Pain assessment in nonverbal older adults with advanced dementia. Perspect Psychiatr Care. 2005 Jul-Sep;41(3):99-113.


National Institute Of Clinical Studies (NICS). Institutional approaches to pain assessment and management. Prepared by the Health Technology Assessment Unit, Department of Public Health, University of Adelaide. 2003;111pp. [No Abstract Available]

Pharmacology: 139 reviews


Makhlouf SM, Pini S, Ahmed S, Bennett MI. Managing Pain in People with Cancer-a Systematic Review of the Attitudes and Knowledge of Professionals, Patients, Caregivers and Public. J Cancer Educ. 2020 Apr;35(2):214-240. doi: 10.1007/s13187-019-01548-9. 


Edler-Buggy S, Birtwistle J, ElMokhallalati Y, Kindl K, Good P, Bennett MI. Regular dosing compared with as-needed dosing of opioids for management of chronic cancer pain: systematic review and meta-analysis. Pain. 2019 Dec 10. doi: 10.1097/j.pain.0000000000001755. [Epub ahead of print]

Erdal A, Ballard C, Vahia IV, Husebo BS. Analgesic treatments in people with dementia - how safe are they? A systematic review. Expert Opin Drug Saf. 2019 Jun;18(6):511-522. doi: 10.1080/14740338.2019.1614166. Epub 2019 May 16.

Häuser W, Welsch P, Klose P, Radbruch L, Fitzcharles MA. Efficacy, tolerability and safety of cannabis-based medicines for cancer pain : A systematic review with meta-analysis of randomised controlled trials. Schmerz. 2019 May 9. doi: 10.1007/s00482-019-0373-3. [Epub ahead of print]


Anshasi HA, Ahmad M. An assessment of methodological quality of systematic reviews of acupuncture and related therapies for cancer-related pain. Complement Ther Clin Pract. 2018 Aug;32:163-168. doi: 10.1016/j.ctcp.2018.06.013. Epub 2018 Jun 30.

Candy B, Jones L, Vickerstaff V, Larkin PJ, Stone P. Mu-opioid antagonists for opioid-induced bowel dysfunction in people with cancer and people receiving palliative care. Cochrane Database Syst Rev. 2018 Jun 5;6:CD006332. doi: 10.1002/14651858.CD006332.pub3. [Epub ahead of print]

Darkovska-Serafimovska M, Serafimovska T, Arsova-Sarafinovska Z, Stefanoski S, Keskovski Z, Balkanov T. Pharmacotherapeutic considerations for use of cannabinoids to relieve pain in patients with malignant diseases. J Pain Res. 2018 Apr 23;11:837-842. doi: 10.2147/JPR.S160556. eCollection 2018.

Giusti R, Bossi P, Mazzotta M, Filetti M, Iacono D, Marchetti P. The use of fentanyl in pain management in head and neck cancer patients: a narrative review. Br J Pain. 2018 Aug;12(3):155-162. doi: 10.1177/2049463717736787. Epub 2017 Oct 10.

Jansen K, Haugen DF, Pont L, Ruths S. Safety and Effectiveness of Palliative Drug Treatment in the Last Days of Life-A Systematic Literature Review. J Pain Symptom Manage. 2018 Feb;55(2):508-521.e3. doi: 10.1016/j.jpainsymman.2017.06.010. Epub 2017 Aug 10.

Johnstone-Petty M. Ketamine Use for Complex Pain in the Palliative Care Population. J Hosp Palliat Nurs. 2018 Dec;20(6):561-567. doi: 10.1097/NJH.0000000000000488.

Mercadante S, Bruera E. Methadone as a First-Line Opioid in Cancer Pain Management: A Systematic Review. J Pain Symptom Manage. 2018 Mar;55(3):998-1003. doi: 10.1016/j.jpainsymman.2017.10.017. Epub 2017 Nov 1.

Nijland L, Schmidt P, Frosch M, Wager J, Hübner-Möhler B, Drake R, Zernikow B. Subcutaneous or intravenous opioid administration by patient-controlled analgesia in cancer pain: a systematic literature review. Support Care Cancer. 2018 Jul 28. doi: 10.1007/s00520-018-4368-x. [Epub ahead of print]

Schmidt-Hansen M, Bennett MI, Arnold S, Bromham N, Hilgart JS. Efficacy, tolerability and acceptability of oxycodone for cancer-related pain in adults: an updated Cochrane systematic review. BMJ Support Palliat Care. 2018 Jun;8(2):117-128. doi: 10.1136/bmjspcare-2017-001457. Epub 2018 Jan 13.

​Shin S, Mitchell C, Mannion K, Smolyn J, Meghani SH. An Integrated Review of Cannabis and Cannabinoids in Adult Oncologic Pain Management. Pain Manag Nurs. 2018 Dec 6. pii: S1524-9042(18)30209-1. doi: 10.1016/j.pmn.2018.09.006. [Epub ahead of print]

Thomas R, Phillips M, Hamilton RJ. Pain Management in the Pediatric Palliative Care Population. J Nurs Scholarsh. 2018 May 5. doi: 10.1111/jnu.12389. [Epub ahead of print]

Xu X, Luckett T, Wang AY, Lovell M, Phillips JL. Cancer pain management needs and perspectives of patients from Chinese backgrounds: a systematic review of the Chinese and English literature. Palliat Support Care. 2018 Jan 17:1-15. doi: 10.1017/S1478951517001171. [Epub ahead of print]



Bell R, Eccleston C, Kalso E. Ketamine as an adjuvant to opioids for cancer pain. Cochrane Database Syst Rev. 2017 Jun 28;6:CD003351. doi: 10.1002/14651858.CD003351.pub3 [Updated review].

Häuser W, Fitzcharles MA, Radbruch L, Petzke F. Cannabinoids in pain management and palliative medicine: an overview of systematic reviews and prospective observational studies. Dtsch Arztebl Int. 2017 Sep 22;114(38):627-634. doi: 10.3238/arztebl.2017.0627.

Macherey S, Monsef I, Jahn F, Jordan K, Yuen KK, Heidenreich A, Skoetz N. Bisphosphonates for advanced prostate cancer. Cochrane Database Syst Rev. 2017 Dec 26;12:CD006250. doi: 10.1002/14651858.CD006250.pub2.

Mercadante S. The role of tapentadol as a strong opioid in cancer pain management: a systematic and critical review. Curr Med Res Opin. 2017 Nov;33(11):1965-1969. doi: 10.1080/03007995.2017.1379981. Epub 2017 Sep 21.

Porta-Sales J, Garzón-Rodríguez C, Llorens-Torromé S, Brunelli C, Pigni A, Caraceni A. Evidence on the analgesic role of bisphosphonates and denosumab in the treatment of pain due to bone metastases: A systematic review within the European Association for Palliative Care guidelines project. Palliat Med. 2017 Jan;31(1):5-25. Epub 2016 Jul 10.

Sande TA, Laird BJ, Fallon MT. The use of opioids in cancer patients with renal impairment-a systematic review. Support Care Cancer. 2017 Feb;25(2):661-675. doi: 10.1007/s00520-016-3447-0. Epub 2016 Oct 15.

van den Beuken-van Everdingen MH, de Graeff A, Jongen JL, Dijkstra D, Mostovaya I, Vissers KC; national guideline working group “Diagnosis treatment of cancer pain”. Pharmacological Treatment of Pain in Cancer Patients: The Role of Adjuvant Analgesics, a Systematic Review. Pain Pract. 2017 Mar;17(3):409-419. doi: 10.1111/papr.12459. Epub 2016 May 21.


Merlin JS, Bulls HW, Vucovich LA, Edelman EJ, Starrels JL. Pharmacologic and non-pharmacologic treatments for chronic pain in individuals with HIV: a systematic review. AIDS Care. 2016 Dec;28(12):1506-1515. Epub 2016 Jun 7.


Beecham E, Candy B, Howard R, McCulloch R, Laddie J, Rees H, Vickerstaff V, Bluebond-Langner M, Jones L. Pharmacological interventions for pain in children and adolescents with life-limiting conditions. Cochrane Database Syst Rev. 2015 Mar 13;3:CD010750.

Guan J, Tanaka S, Kawakami K. Anticonvulsants or Antidepressants in Combination Pharmacotherapy for Treatment of Neuropathic Pain in Cancer Patients: A Systematic Review and Meta-analysis. Clin J Pain. 2016 Aug;32(8):719-25.

Hendriks LE, Hermans BC, van den Beuken-van Everdingen MH, Hochstenbag MM, Dingemans AM. Effect of Bisphosphonates, Denosumab, and Radioisotopes on Bone Pain and Quality of Life in Patients with Non-Small Cell Lung Cancer and Bone Metastases: A Systematic Review. J Thorac Oncol. 2016 Feb;11(2):155-73. Epub 2015 Dec 22.

Kotlinska-Lemieszek A, Klepstad P, Haugen DF. Clinically significant drug-drug interactions involving opioid analgesics used for pain treatment in patients with cancer: a systematic review. Drug Des Devel Ther. 2015 Sep 16;9:5255-67.eCollection 2015.

Kurita GP, Benthien KS, Nordly M, Mercadante S, Klepstad P, Sjøgren P; European Palliative Care Research Collaborative (EPCRC). The evidence of neuraxial administration of analgesics for cancer-related pain: a systematic review. Acta Anaesthesiol Scand. 2015 Oct;59(9):1103-15. Epub 2015 Feb 13.

McLean S, Twomey F. Methods of Rotation From Another Strong Opioid to Methadone for the Management of Cancer Pain: A Systematic Review of the Available Evidence. J Pain Symptom Manage. 2015 Aug;50(2):248-259.e1.

Schmidt-Hansen M, Bromham N, Taubert M, Arnold S, Hilgart JS. Buprenorphine for treating cancer pain. Cochrane Database Syst Rev. 2015 Mar 31;3:CD009596.

Wiffen PJ, Derry S, Moore RA. Impact of morphine, fentanyl, oxycodone or codeine on patient consciousness, appetite and thirst when used to treat cancer pain. Cochrane Database Syst Rev. 2014 May 29;5:CD011056.

Wiffen PJ, Derry S, Naessens K, Bell RF. Oral tapentadol for cancer pain. Cochrane Database Syst Rev. 2015 Sep 25;(9):CD011460. CD011460.pub2.


Fontes AS, Gonçalves JF. Pain treatment in patients infected with human immunodeficiency virus in later stages: pharmacological aspects. Am J Hosp Palliat Care. 2014 Mar;31(2):194-201. doi: 10.1177/1049909113480553. Epub 2013 Mar 15.

Mesgarpour B, Griebler U, Glechner A, Kien C, Strobelberger M, Van Noord MG, Michalek-Sauberer A. Extended-release opioids in the management of cancer pain: a systematic review of efficacy and safety. Eur J Pain. 2014 May;18(5):605-16.Epub 2013 Sep 20.


Brettschneider J, Kurent J, Ludolph A. Drug therapy for pain in amyotrophic lateral sclerosis or motor neuron disease. Cochrane Database Syst Rev. 2013 Jun 5;6:CD005226.

Jandhyala R, Fullarton JR, Bennett MI. Efficacy of rapid-onset oral fentanyl formulations vs. oral morphine for cancer-related breakthrough pain: a meta-analysis of comparative trials. 2013 Oct;46(4):573-80. Epub 2013 Feb 4.

Jongen JL, Huijsman ML, Jessurun J, Ogenio K, Schipper D, Verkouteren DR, Moorman PW, van der Rijt CC, Vissers KC. The evidence for pharmacologic treatment of neuropathic cancer pain: beneficial and adverse effects. J Pain Symptom Manage. 2013 Oct;46(4):581-590. Epub 2013 Feb 12.

López-Saca JM, Guzmán JL, Centeno C. A systematic review of the influence of opioids on advanced cancer patient survival. Curr Opin Support Palliat Care. 2013 Dec;7(4):424-30.

Paulsen Ø, Aass N, Kaasa S, Dale O. Do corticosteroids provide analgesic effects in cancer patients? A systematic literature review. J Pain Symptom Manage. 2013 Jul;46(1):96-105.Epub 2012 Nov 11.


Hansen MS, Mathiesen O, Trautner S, Dahl JB. Intranasal fentanyl in the treatment of acute pain - a systematic review. Acta Anaesthesiol Scand. 2012 Apr;56(4):407-19. doi: 10.1111/j.1399-6576.2011.02613.x. Epub 2012 Jan 19.

Mercadante S, Bruera E. The effect of age on opioid switching to methadone: a systematic review. J Palliat Med. 2012 Mar;15(3):347-51. Epub 2012 Feb 21.

Minozzi S, Amato L, Davoli M. Development of dependence following treatment with opioid analgesics for pain relief: a systematic review. Addiction. 2012 Jul 6. doi: 10.1111/j.1360-0443.2012.04005.x. [Epub ahead of print]

Nabal M, Librada S, Redondo MJ, Pigni A, Brunelli C, Caraceni A. The role of paracetamol and nonsteroidal anti-inflammatory drugs in addition to WHO Step III opioids in the control of pain in advanced cancer. A systematic review of the literature. Palliat Med. 2012 Jun;26(4):305-12. Epub 2011 Nov 29.

Wong MH, Stockler MR, Pavlakis N. Bisphosphonates and other bone agents for breast cancer. Cochrane Database Syst Rev. 2012 Feb 15;(2):CD003474.


Bekkering GE, Soares-Weiser K, Reid K, Kessels AG, Dahan A, Treede RD, Kleijnen J. Can morphine still be considered to be the standard for treating chronic pain? A systematic review including pair-wise and network meta-analyses. Curr Med Res Opin. 2011 Jul;27(7):1477-91. Epub 2011 Jun 2.

Bennett MI. Effectiveness of antiepileptic or antidepressant drugs when added to opioids for cancer pain: systematic review. Palliat Med. 2011 Jul;25(5):553-9. Epub 2010 Jul 29.

Caraceni A, Pigni A, Brunelli C. Is oral morphine still the first choice opioid for moderate to severe cancer pain? A systematic review within the European Palliative Care Research Collaborative guidelines project. Palliat Med. 2011 July 1;25(5):402-9.

Cherny N. Is oral methadone better than placebo or other oral/transdermal opioids in the management of pain? Palliat Med. 2011 Jul;25(5):488-93.

Dale O, Moksnes K, Kaasa S. European Palliative Care Research Collaborative pain guidelines: Opioid switching to improve analgesia or reduce side effects. A systematic review. Palliat Med. 2011 Jul;25(5):494-503.

Davis MP. Fentanyl for breakthrough pain: a systematic review. Expert Rev Neurother. 2011 Aug;11(8):1197-216.

Elsner F, Zeppetella G, Porta-Sales J, Tagarro I. Newer generation fentanyl transmucosal products for breakthrough pain in opioid-tolerant cancer patients. Clin Drug Investig. 2011;31(9):605-18.

Fallon MT, Laird BJA. A systematic review of combination step III opioid therapy in cancer pain: An EPCRC opioid guideline project. Palliat Med. 2011 Jul;25(5):597-603.

King S, Forbes K, Hanks GW, Ferro CJ, Chambers EJ. A systematic review of the use of opioid medication for those with moderate to severe cancer pain and renal impairment: A European Palliative Care Research Collaborative opioid guidelines project. Palliat Med. 2011 Jul;25(5):525-52.

King SJ, Reid C, Forbes K, Hanks G. A systematic review of oxycodone in the management of cancer pain. Palliat Med. 2011 Jul;25(5):454-70.

Klepstad Pl, Kaasa S, Borchgrevink PC. Starting Step III opioids for moderate to severe pain in cancer patients: Dose titration: A systematic review. Palliat Med. 2011 Jul;25(5):424-30.

Kurita GP, Kaasa S, Sjogren P. Spinal opioids in adult patients with cancer pain: A systematic review: A European Palliative Care Research Collaborative (EPCRC) Opioid Guidelines Project. Palliat Med. 2011 Jul;25(5):560-77.

Matthews ML, Lufkin R. Tapentadol: a novel, centrally acting analgesic for moderate-to-severe acute pain. J Pharm Technol. 2011 Jan-Feb;27(1):27-34.

Mercadante S, Caraceni A. Conversion ratios for opioid switching in the treatment of cancer pain: a systematic review. Palliat Med. 2011 Jul;25(5):504-15.

Pigni A, Brunelli C, Caraceni A. The role of hydromorphone in cancer pain treatment: a systematic review. Palliat Med. 2011 Jul;25(5):471-7.

Radbruch L, Trottenberg P, Elsner F, Kaasa S, Caraceni A. Systematic review of the role of alternative application routes for opioid treatment for moderate to severe cancer pain: An EPCRC opioid guidelines project. Palliat Med. 2011 Jul;25(5):578-96.

Ramasubbu C, Gupta A. Pharmacological treatment of opioid-induced hyperalgesia: a review of the evidence. J Pain Palliat Care Pharmacother. 2011;25(3):219-30. Epub 2011 Aug 11.

Tassinari D, Drudi F, Rosati M, Maltoni M. Transdermal opioids as front line treatment of moderate to severe cancer pain: a systemic review. Palliat Med. 2011 Jul;25(5):478-87.

Tassinari D, Drudi F, Rosati M, Tombesi P, Sartori S, Maltoni M. The second step of the analgesic ladder and oral tramadol in the treatment of mild to moderate cancer pain: A systematic review. Palliat Med. 2011 Jul;25(5):410-23.

Tomlinson D, von Baeyer CL, Stinson JN, Sung L. A systematic review of faces scales for the self-report of pain intensity in children. Pediatrics. 2010 Nov;126(5):e1168-98. Epub 2010 Oct 4.

Webster LR, Cochella S, Dasgupta N, Fakata KL, Fine PG, Fishman SM, Grey T, Johnson EM, Lee LK, Passik SD, Peppin J, Porucznik CA, Ray A, Schnoll SH, Stieg RL, Wakeland W. An analysis of the root causes for opioid-related overdose deaths in the United States. Pain Med. 2011 Jun;12 Suppl 2:S26-35. doi: 10.1111/j.1526-4637.2011.01134.x.

Zeppetella G. Opioids for the management of breakthrough cancer pain in adults: A systematic review undertaken as part of an EPCRC opioid guidelines project. Palliat Med. 2011 Jul;25(5):516-24.


Flemming K. The use of morphine to treat cancer-related pain: a synthesis of quantitative and qualitative research. J Pain Symptom Manage. 2010 Jan;39(1):139-54. Epub 2009 Sep 24.

Mayyas F, Fayers P, Kaasa S, Dale O. A systematic review of oxymorphone in the management of chronic pain. J Pain Symptom Manage. 2010 Feb;39(2):296-308.

Niesters M, Dahan A, Kest B, Zacny J, Stijnen T, Aarts L, Sarton E. Do sex differences exist in opioid analgesia? A systematic review and meta-analysis of human experimental and clinical studies. Pain. 2010 Oct;151(1):61-8. Epub 2010 Aug 9.

Noble M, Treadwell JR, Tregear SJ, Coates VH, Wiffen PJ, Akafomo C, Schoelles KM. Long-term opioid management for chronic noncancer pain. Cochrane Database Syst Rev. 2010 Jan 20;(1):CD006605.

Papaleontiou M, Henderson CR Jr, Turner BJ, Moore AA, Olkhovskaya Y, Amanfo L, Reid MC. Outcomes associated with opioid use in the treatment of chronic noncancer pain in older adults: a systematic review and meta-analysis. J Am Geriatr Soc. 2010 Jul;58(7):1353-69. Epub 2010 Jun 1.

Park J, Castellanos-Brown K, Belcher J. A review of observational pain scales in nonverbal elderly with cognitive impairments. Research on Social Work Practice. 2010;20(6):651-4.

Pigni A, Brunelli C, Gibbins J, Hanks G, Deconno F, Kaasa S, Klepstad P, Radbruch L, Caraceni A. Content development for EUROPEAN GUIDELINES on the use of opioids for cancer pain: a systematic review and Expert Consensus Study. Minerva Anestesiol. 2010 Oct;76(10):833-43.

Plested M, Budhia S, Gabriel Z. Pregabalin, the lidocaine plaster and duloxetine in patients with refractory neuropathic pain: a systematic review. BMC Neurol. 2010;10:116.

Saarto T, Wiffen PJ. Antidepressants for neuropathic pain: a Cochrane review. J Neurol Neurosurg Psychiatry. 2010 Dec;81(12):1372-3. Epub 2010 Jun 11. No abstract available.

Varrassi G, Müller-Schwefe G, Pergolizzi J, Orónska A, Morlion B, Mavrocordatos P, Margarit C, Mangas C, Jaksch W, Huygen F, Collett B, Berti M, Aldington D, Ahlbeck K. Pharmacological treatment of chronic pain - the need for CHANGE. Curr Med Res Opin. 2010 May;26(5):1231-45.

Vissers D, Stam W, Nolte T, Lenre M, Jansen J. Efficacy of intranasal fentanyl spray versus other opioids for breakthrough pain in cancer. Curr Med Res Opin. 2010 May;26(5):1037-45.

Vissers KC, Besse K, Hans G, Devulder J, Morlion B. Opioid rotation in the management of chronic pain: where is the evidence? Pain Pract. 2010 Mar-Apr;10(2):85-93. Epub 2010 Jan 8.

Yang Q, Xie DR, Jiang ZM, Ma W, Zhang YD, Bi ZF, Chen DL. Efficacy and adverse effects of transdermal fentanyl and sustained-release oral morphine in treating moderate-severe cancer pain in Chinese population: a systematic review and meta-analysis. J Exp Clin Cancer Res. 2010 Jun 9;29:67.


Aiello-Laws L, Reynolds J, Deizer N, Peterson M, Ameringer S, Bakitas M. Putting evidence into practice: what are the pharmacologic interventions for nociceptive and neuropathic cancer pain in adults? Clin J Oncol Nurs. 2009 Dec;13(6):649-55.

Goodyear-Smith F, Halliwell J. Anticonvulsants for neuropathic pain: gaps in the evidence. Clin J Pain. 2009 Jul-Aug;25(6):528-36.

Pergolizzi JV Jr, Mercadante S, Echaburu AV, Van den Eynden B, Fragoso RM, Mordarski S, Lybaert W, Beniak J, Orońska A, Slama O; Euromed Communications meeting. The role of transdermal buprenorphine in the treatment of cancer pain: an expert panel consensus. Curr Med Res Opin. 2009 Jun;25(6):1517-28.

Shaheen PE, Walsh D, Lasheen W, Davis MP, Lagman RL. Opioid equianalgesic tables: are they all equally dangerous? J Pain Symptom Manage. 2009 Sep;38(3):409-17.

Tassinari D, Sartori S, Tamburini E, Scarpi E, Tombesi P, Santelmo C, Maltoni M. Transdermal fentanyl as a front-line approach to moderate-severe pain: a meta-analysis of randomized clinical trials. J Palliat Care. 2009 Autumn;25(3):172-80.


Cade CH. Clinical tools for the assessment of pain in sedated critically ill adults. Nurs Crit Care. 2008 Nov-Dec;13(6):288-97.

Cruciani RA. Methadone: to ECG or not to ECG...That is still the question. J Pain Symptom Manage. 2008 Nov;36(5):545-52. Epub 2008 Apr 28.

Leonard R. Too much of a good thing? Treating the emerging syndrome of opioid-induced hyperalgesia. J Pharm Pract. 2008 Apr;21(2):165-8.

Quigley C. Opioids in people with cancer-related pain. Clin Evid (Online). 2008 Jul 31;2008. pii: 2408

Riley J, Eisenberg E, Müller-Schwefe G, Drewes AM, Arendt-Nielsen L. Oxycodone: a review of its use in the management of pain. Curr Med Res Opin. 2008 Jan;24(1):175-92.

Seidel S, Aigner M, Ossege M, Pernicka E, Wildner B, Sycha T. Antipsychotics for acute and chronic pain in adults. Cochrane Database Syst Rev. 2008 Oct 8;(4):CD004844.

Skorpen F, Laugsand EA, Klepstad P, Kaasa S. Variable response to opioid treatment: any genetic predictors within sight? Palliat Med. 2008 Jun;22(4):310-27.

Tassinari D, Sartori S, Tambiurini E, Scarpi E, Raffaeli W, Tombesi P, Maltoni M. Adverse effects of transdermal opiates treating moderate-severe cancer pain in comparison to long-acting morphine: a meta-analysis and systematic review of the literature. J Palliat Med. 2008 May-Jun;11(3):492-501.

Wang T, Collet JP, Shapiro S, Ware MA. Adverse effects of medical cannabinoids: a systematic review. CMAJ. 2008 Jun 17;178(13):1669-78.

Weschules DJ, Bain KT. A systematic review of opioid conversion ratios used with methadone for the treatment of pain. Pain Med. 2008 9(5):595-612. Epub 2008 Jun 28.


Dulko D. Audit and feedback as a clinical practice guideline implementation strategy: a model for acute care nurse practitioners. Worldviews Evid Based Nurs. 2007;4(4):200-9.

Dworkin RH, O'Connor AB, Backonja M, Farrar JT, Finnerup NB, Jensen TS, Kalso EA, Loeser JD, Miaskowski C, Nurmikko TJ, Portenoy RK, Rice AS, Stacey BR, Treede RD, Turk DC, Wallace MS. Pharmacologic management of neuropathic pain: evidence-based recommendations. Pain. 2007 Dec 5;132(3):237-51. Epub 2007 Oct 24.

Gøtzsche PC. NSAIDs. Clin Evid (Online). 2007 Jun 1;2007. pii: 1108.

Nicholson AB. Methadone for cancer pain. Cochrane Database Syst Rev. 2007 Oct 17(4):CD003971. [Updated 2017]

Saarto T, Wiffen PJ. Antidepressants for neuropathic pain. Cochrane Database Syst Rev. 2007 Oct 17;(4):CD005454.

Wiffen PJ, McQuay HJ. Oral morphine for cancer pain. Cochrane Database Syst Rev. 2007 Oct 17;(4):CD003868.

Wiffen PJ, Rees J. Lamotrigine for acute and chronic pain. Cochrane Database Syst Rev. 2007 Apr 18;(2):CD006044. [Updated 2011]

Xu L, Lao LX, Ge A, Yu S, Li J, Mansky PJ. Chinese herbal medicine for cancer pain. Integr Cancer Ther. 2007 Sep;6(3):208-34.


Dühmke RM, Hollingshead J, Cornblath DR. Tramadol for neuropathic pain. Cochrane Database Syst Rev. 2006 Jul 19;(3):CD003726. [Updated 2017]

Eisenberg E, McNicol ED, Carr DB. Opioids for neuropathic pain. Cochrane Database Syst Rev. 2006 Jul 19;(3):CD006146.

Legge J, Ball N, Elliott DP. The potential role of ketamine in hospice analgesia: a literature review. Consult Pharm. 2006 Jan;21(1):51-7.

Martinez-Zapata MJ, Roqué M, Alonso-Coello P, Català E. Calcitonin for metastatic bone pain. Cochrane Database  Syst Rev. 2006 Jul 19;(3):CD003223.

Mercadante S, Bruera E. Opioid switching: A systematic and critical review. Cancer Treat Rev. 2006 Jun;32(4):304-15. Epub 2006 Apr 19.

Reid CM, Martin RM, Sterne JAC, Davies AN, Hanks GW. Oxycodone for cancer-related pain: meta-analysis of randomized controlled trials. Arch Intern Med. 2006 Apr 24;166(8):837-43.

Tatrow K, Montgomery GH. Cognitive behavioral therapy techniques for distress and pain in breast cancer patients: a meta-analysis. J Behav Med. 2006 Feb;29(1):17-27. Epub 2006 Jan 7.

Yuen KK, Shelley M, Sze WM, Wilt T, Mason MD. Bisphosphonates for advanced prostate cancer. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD006250. [Updated 2017] 

Zeppetella G, Ribeiro MD. Opioids for the management of breakthrough (episodic) pain in cancer patients. Cochrane Database Syst Rev. 2006 Jan 25;(1):CD004311.

Zwakhalen SM, Hamers JP, Abu-Saad HH, Berger MP. Pain in elderly people with severe dementia: a systematic review of behavioural pain assessment tools. BMC Geriatr. 2006 Jan 27;6:3.


Bauman G, Charette M, Reid R, Sathya J. Radiopharmaceuticals for the palliation of painful bone metastasis-a systemic review. Radiother Oncol. 2005 Jun;75(3):258-70.

Challapalli V, Tremont-Lukats IW, McNicol ED, Lau J, Carr DB. Systemic administration of local anesthetic agents to relieve neuropathic pain. Cochrane Database Syst Rev. 2005 Oct 19;(4):CD003345.

McNicol E, Strassels SA, Goudas L, Lau J, Carr DB. NSAIDS or paracetamol, alone or combined with opioids, for cancer pain. Cochrane Database Syst Rev. 2005 Apr 20;(2):CD005180. [Withdrawn 2015]

Moore RA, McQuay HJ. Prevalence of opioid adverse events in chronic non-malignant pain: systematic review of randomised trials of oral opioids. Arthritis Res Ther. 2005;7(5):R1046-51. Epub 2005 Jun 28.

Pavlakis N, Schmidt R, Stockler M. Bisphosphonates for breast cancer. Cochrane Database Syst Rev. 2005 Jul 20;(3):CD003474 [Updated 2012].

Wiffen P, Collins S, McQuay H, Carroll D, Jadad A, Moore A. Anticonvulsant drugs for acute and chronic pain. Cochrane Database Syst Rev. 2005 Jul 20;(3):CD001133. [WITHDRAWN]

Wiffen PJ, McQuay HJ, Edwards JE, Moore RA. Gabapentin for acute and chronic pain. Cochrane Database Syst Rev. 2005 Jul 20;(3):CD005452. [WITHDRAWN]

Wiffen PJ, McQuay HJ, Moore RA. Carbamazepine for acute and chronic pain. Cochrane Database Syst Rev. 2005 Jul 20;(3):CD005451 [Updated 2014].


Anderson SL, Shreve ST. Continuous subcutaneous infusion of opiates at end-of-life. Ann Pharmacother. 2004 Jun;38(6):1015-23. Epub 2004 Apr 30.

Davis MP, Weissman DE, Arnold RM. Opioid dose titration for severe cancer pain: a systematic evidence-based review. J Palliat Med. 2004 Jun;7(3):462-8.

Quigley C. Opioid switching to improve pain relief and drug tolerability. Cochrane Database Syst Rev. 2004;(3):CD004847.

Wootton M. Morphine is not the only analgesic in palliative care: literature review. J Adv Nurs. 2004 Mar;45(5):527-32.


Bell R, Eccleston C, Kalso E. Ketamine as an adjuvant to opioids for cancer pain. Cochrane Database Syst Rev. 2003;(1):CD003351 [Updated 2012]. 

Chou, R, Clark, E, Helfand, M. Comparative efficacy and safety of long-acting oral opioids for chronic non-cancer pain: a systematic review. J Pain Symptom Manage. 2003 Nov;26(5)1026-48.

Fishbain DA, Cutler RB, Rosomoff HL, Rosomoff RS. Are opioid-dependent/tolerant patients impaired in driving-related skills? a structured evidence-based review. J Pain Symptom Manage. 2003 Jun;25(6):559-77.

Jensen MP. The validity and reliability of pain measures in adults with cancer. J Pain. 2003 Feb;4(1):2-21.

McNicol E, Horowicz-Mehler N, Fisk RA, Bennett K, Gialeli-Goudas M, Chew PW, Lau J, Carr D; Americal Pain Society. Management of opioid side effects in cancer-related and chronic noncancer pain: a systematic review. J Pain. 2003 Jun;4(5):231-56.

Quigley C, Wiffen P. A systematic review of hydromorphone in acute and chronic pain. J Pain Symptom Manage. 2003 Feb;25(2):169-78.

Djulbegovic B, Wheatley K, Ross J, Clark O, Bos G, Goldschmidt H, Cremer F, Alsina M, Glasmacher A. Bisphosphonates in multiple myeloma. Cochrane Database Syst Rev. 2002;(4):CD003188. [Updated 2010]


Wong R, Wiffen PJ. Bisphosphonates for the relief of pain secondary to bone metastases. Cochrane Database Syst Rev. 2002;(2):CD002068.


Cairns R. The use of oxycodone in cancer-related pain: a literature review. Int J Palliat Nurs. 2001 Nov;7(11):522-7.

Pereira J, Lawlor P, Vigano A, Dorgan M, Bruera E. Equianalgesic dose ratios for opioids: A critical review and proposals for long-term dosing. J Pain Symptom Manage. 2001 Aug;22(2):672-87.

Mannix K, Ahmedzai SH, Anderson H, Bennett M, Lloyd-Williams M, Wilcock A. Using bisphosphonates to control the pain of bone metastases: evidence-based guidelines for palliative care. Palliat Med. 2000 Nov;14(6):455-61.

Last updated 01 July 2020