Review collection - Symptom and clinical dilemmas 

131 reviews


Beheshtaeen F, Torabizadeh C, Khaki S, Abshorshori N, Vizeshfar F. Moral distress among critical care nurses before and during the covid-19 pandemic: A systematic review. Nurs Ethics. 2023 Dec 20:9697330231221196.

Cappucci SP, Smith WS, Schwartzstein R, White DB, Mitchell SL, Fehnel CR. End-Of-Life Care in the Potential Donor after Circulatory Death: A Systematic Review. Neurohospitalist. 2023 Jan;13(1):61-68. doi: 10.1177/19418744221123194. Epub 2022 Oct 9.

Del Nero L, Sheijani AD, De Ceglie A, Bruzzone M, Ceppi M, Filiberti RA, Siersema P, Conio M. A Meta-Analysis of Endoscopic Stenting Versus Surgical Treatment for Malignant Gastric Outlet Obstruction. World J Surg. 2023 Mar 3. doi: 10.1007/s00268-023-06944-3. Epub ahead of print.

Hammond L, Chakraborty A, Thorpe C, O'Loughlin M, Allcroft P, Phelan C. Relieving Perception of Thirst and Xerostomia in Patients with Palliative and End-of-life Care Needs: A Rapid Review. J Pain Symptom Manage. 2023 Jul;66(1):e45-e68. doi: 10.1016/j.jpainsymman.2023.02.315. Epub 2023 Feb 23.

Mazzu MA, Campbell ML, Schwartzstein RM, White DB, Mitchell SL, Fehnel CR. Evidence Guiding Withdrawal of Mechanical Ventilation at the End of Life: A Review. J Pain Symptom Manage. 2023 May 26:S0885-3924(23)00517-1. doi: 10.1016/j.jpainsymman.2023.05.009. Epub ahead of print.

Obarzanek L, Wu W, Tutag-Lehr V. Opioid Management of Dyspnea at End of Life: A Systematic Review. J Palliat Med. 2023 May;26(5):711-726. doi: 10.1089/jpm.2022.0311. Epub 2022 Nov 28.

Ramsburg H, Moriarty HJ, MacKenzie Greenle M. End-of-Life Symptoms in Adult Patients With Stroke in the Last Two Years of Life: An Integrative Review. Am J Hosp Palliat Care. 2023 Aug 24:10499091231197657. doi: 10.1177/10499091231197657. Epub ahead of print.

Salazar J, Bracchiglione J, Savall-Esteve O, Antequera A, Bottaro-Parra D, Gutiérrez-Valencia M, Martínez-Peralta S, Pericay C, Tibau A, Bonfill X; Appropriateness of Systemic Oncological Treatments for Advanced Cancer (ASTAC) Research Group. Treatment with anticancer drugs for advanced pancreatic cancer: a systematic review. BMC Cancer. 2023 Aug 12;23(1):748. doi: 10.1186/s12885-023-11207-4.

Tan F, Li N, Wu Y, Zhang C. Palliative sedation determinants: systematic review and meta-analysis in palliative medicine. BMJ Support Palliat Care. 2023 Aug 8:spcare-2022-004085. doi: 10.1136/spcare-2022-004085. Epub ahead of print.

Zhong Y, Cavolo A, Labarque V, Gastmans C. Physicians' attitudes and experiences about withholding/withdrawing life-sustaining treatments in pediatrics: A systematic review of quantitative evidence. BMC Palliat Care. 2023 Sep 29;22(1):145.


Akid I, Nesbit S, Nanavati J, Bienvenu OJ, Smith TJ. Prevention of Steroid-Induced Neuropsychiatric Complications With Neuroleptic Drugs: A Review. Am J Hosp Palliat Care. 2022 Apr;39(4):472-476. doi: 10.1177/10499091211034771. Epub 2021 Aug 13.

Baddeley E, Mann M, Bravington A, Johnson MJ, Currow D, Murtagh FEM, Boland EG, Obita G, Oliver A, Seddon K, Nelson A, Boland JW, Noble SIR. Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: A qualitative systematic review. Palliat Med. 2022 Mar 8:2692163221081331. doi: 10.1177/02692163221081331. Epub ahead of print.

Chapman C, Bayes S, Sim M. Communication surrounding initiation and withdrawal of non-invasive ventilation in adults with motor neurone disease. Int J Palliat Nurs. 2022 Jul 2;28(7):298-306. doi: 10.12968/ijpn.2022.28.7.298.

Dhaliwal JS, Talip T, Rajam DT, Dhaliwal SKS, Murang ZR, Ming LC, Venkatasalu MR. A systematic review of interventional studies on oral care of palliative patients. Ann Palliat Med. 2022 Sep;11(9):2980-3000. doi: 10.21037/apm-22-215. Epub 2022 Aug 31.

Doppen DM, Kung DS, Maijers DI, John DM, Dunphy DH, Townsley DH, Eathorne MA, Semprini PA, Braithwaite PI. Cannabis in palliative care: a systematic review of current evidence. J Pain Symptom Manage. 2022 Jun 12:S0885-3924(22)00760-6. doi: 10.1016/j.jpainsymman.2022.06.002. Epub ahead of print.

Fabian A, Domschikowski J, Letsch A, Schmalz C, Freitag-Wolf S, Dunst J, Krug D. Clinical Endpoints in Trials of Palliative Radiotherapy: a Systematic Meta-Research Analysis. Radiother Oncol. 2022 Jul 19:S0167-8140(22)04209-8. doi: 10.1016/j.radonc.2022.07.013. Epub ahead of print.

Fairbairn L, Schuberth A, Deacon L, Gilkes H, Montgomery V, Bennett MI, Mulvey MR. A systematic review of subcutaneous versus intramuscular or intravenous routes of opioid administration on pain outcomes in cancer and post-surgical clinical populations – challenging current assumptions in palliative care practice. Br J Pain. 2022;0(0). doi:10.1177/20494637221135835

Kermavnar T, Guttridge C, Mulcahy NJ, Duffy E, Twomey F, O'Sullivan L. 3D printing in palliative medicine: systematic review. BMJ Support Palliat Care. 2022 Sep 6:bmjspcare-2021-003196. doi: 10.1136/bmjspcare-2021-003196

Kopecky K, Monton O, Rosman L, Johnston F. Palliative interventions for patients with advanced gastric cancer: a systematic review. Chin Clin Oncol. 2022 Dec;11(6):47. doi: 10.21037/cco-22-102.

Latimer S, Walker RM, Ray-Barruel G, Shaw J, Mackrell K, Hunt T, Gillespie BM. Defining and Describing Terminal Ulcers in Adults at End of Life: An Integrative Review. Adv Skin Wound Care. 2022 Apr 1;35(4):225-233. doi: 10.1097/01.ASW.0000798032.98853.95.

Lucena A, Yuguero O. Systematic Review of Common Refractory Symptoms in the End-Of-Life Situation and Its Relation With Euthanasia. Omega (Westport). 2022 Apr 20:302228221089123. doi: 10.1177/00302228221089123. Epub ahead of print.

Mohan BP, Chandan S, Khan SR, Kassab LL, Ponnada S, Artifon ELA, Otoch JP, McDonough S, Adler DG. Photodynamic Therapy (PDT), Radiofrequency Ablation (RFA) With Biliary Stents in Palliative Treatment of Unresectable Extrahepatic Cholangiocarcinoma: A Systematic Review and Meta-analysis. J Clin Gastroenterol. 2022 Feb 1;56(2):e153-e160. doi: 10.1097/MCG.0000000000001524.

O'Brien J, Dingle M. A dual realist review: Compression for leg swelling at the end of life has potential quality of life benefit. J Adv Nurs. 2022 Dec;78(12):4003-4018. doi: 10.1111/jan.15458. Epub 2022 Oct 13.

Perna A, Smakaj A, Vitiello R, Velluto C, Proietti L, Tamburrelli FC, Maccauro G. Posterior Percutaneous Pedicle Screws Fixation Versus Open Surgical Instrumented Fusion for Thoraco-Lumbar Spinal Metastases Palliative Management: A Systematic Review and Meta-analysis. Front Oncol. 2022 Apr 4;12:884928. doi: 10.3389/fonc.2022.884928.

Song S, Gong S, Lei T, Tian H, Lu T, Lei C, Jin H, Yang W, Yang K, Guo T. Comparative efficacy and safety of local palliative therapeutics for unresectable malignant biliary obstruction: a Bayesian network meta-analysis. Expert Rev Gastroenterol Hepatol. 2022 Jun;16(6):555-567. doi: 10.1080/17474124.2022.2085090. Epub 2022 Jun 14.

Song S, Jin H, Cheng Q, Gong S, Lv K, Lei T, Tian H, Li X, Lei C, Yang W, Yang K, Guo T. Local palliative therapies for unresectable malignant biliary obstruction: radiofrequency ablation combined with stent or biliary stent alone? An updated meta-analysis of nineteen trials. Surg Endosc. 2022 Mar 16. doi: 10.1007/s00464-022-09181-2. Epub ahead of print.

Wenzel D, Bleazard L, Pepper CJ, Wilson E, Faull C. Non-invasive advanced respiratory support in end-of-life care and symptom management: systematic review. BMJ Support Palliat Care. 2022 Oct 13:spcare-2022-003905. doi: 10.1136/spcare-2022-003905. Epub ahead of print.

Zeng C, Zhang Y, Yang H, Hong J. Prevention of pancreatitis after stent implantation for distal malignant biliary strictures: systematic review and meta-analysis. Expert Rev Gastroenterol Hepatol. 2022 Jan 21:1-14. doi: 10.1080/17474124.2022.2027239. Epub ahead of print.

Zhao CL, Gu B, Huo XB, Xia FF. I-125 seed-loaded versus normal stent insertion for obstructive esophageal cancer: a meta-analysis. Wideochir Inne Tech Maloinwazyjne. 2021 Dec;16(4):633-640. doi: 10.5114/wiitm.2021.104205. Epub 2021 Mar 8.


Almeida AR, Santana RF, Brandão MAG. Compromised end-of-life syndrome: Concept development from the condition of adults and older adults in palliative care. Int J Nurs Knowl. 2021 Sep 21. doi: 10.1111/2047-3095.12344. Epub ahead of print.

Alves RV. The effectiveness of subcutaneous furosemide for symptoms related to congestion in adults with heart failure: A limited systematic review. Med Palliat. 2021 Feb 10. doi: 10.1016/j.medpal.2020.06.008

Cadogan CA, Murphy M, Boland M, Bennett K, McLean S, Hughes C. Prescribing practices, patterns, and potential harms in patients receiving palliative care: A systematic scoping review. Explor Res Clin Soc Pharm. 2021 Jul 23;3:100050. doi: 10.1016/j.rcsop.2021.100050.

Carter C, Leanza F, Mohammed S, Upshur REG, Kontos P. A rapid scoping review of end-of-life conversations with frail older adults in Canada. Can Fam Physician. 2021 Nov;67(11):e298-e305. doi: 10.46747/cfp.6711e298.

Doosti-Irani A, Mansournia MA, Cheraghi Z, Rahimi-Foroushani A, Haddad P, Holakouie-Naieni K. Network meta-analysis of palliative treatments in patients with esophageal cancer. Crit Rev Oncol Hematol. 2021 Nov 2;168:103506. doi: 10.1016/j.critrevonc.2021.103506. Epub ahead of print.

Feliciano JL, Waldfogel JM, Sharma R, Zhang A, Gupta A, Sedhom R, Day J, Bass EB, Dy SM. Pharmacologic Interventions for Breathlessness in Patients With Advanced Cancer: A Systematic Review and Meta-analysis. JAMA Netw Open. 2021 Feb 1;4(2):e2037632. doi: 10.1001/jamanetworkopen.2020.37632.

Hardy J, Haywood A, Rickett K, Sallnow L, Good P. Practice review: Evidence-based quality use of corticosteroids in the palliative care of patients with advanced cancer. Palliat Med. 2021 Mar;35(3):461-472. doi: 10.1177/0269216320986717. Epub 2021 Jan 27.

Kamalumpundi V, Saeidzadeh S, Chi NC, Nair R, Gilbertson-White S. The efficacy of web or mobile-based interventions to alleviate emotional symptoms in people with advanced cancer: a systematic review and meta-analysis. Support Care Cancer. 2021 Nov 4. doi: 10.1007/s00520-021-06496-z. Epub ahead of print.

Kastelijn JB, van der Loos MA, Welsing PM, Dhondt E, Koopman M, Moons LM, Vleggaar FP. Clinical outcomes of biliary drainage of malignant biliary obstruction due to colorectal cancer metastases: A systematic review. Eur J Intern Med. 2021 Apr 27:S0953-6205(21)00104-7. doi: 10.1016/j.ejim.2021.03.032. Epub ahead of print.

Lau J, Mazzotta P, Fazelzad R, Ryan S, Tedesco A, Smith AJ, Sud A, Furlan AD, Zimmermann C. Assessment tools for problematic opioid use in palliative care: A scoping review. Palliat Med. 2021 May 17:2692163211015567. doi: 10.1177/02692163211015567. Epub ahead of print.

Laurentius A, Wiyono L, Subali AD, Siagian SN. Evaluation of Right Ventricular Outflow Tract Stenting as Palliative Treatment in Severely Cyanotic Tetralogy of Fallot: A Systematic Review and Meta-analysis of Observational Studies. J Tehran Univ Heart Cent. 2021; 16(4): 135-146. doi: 10.18502/jthc.v16i4.8599.

Lee KC, Sokas CM, Streid J, Senglaub SS, Coogan K, Walling AM, Cooper Z. Quality indicators in surgical palliative care: a systematic review. J Pain Symptom Manage. 2021 Jan 29:S0885-3924(21)00143-3. doi: 10.1016/j.jpainsymman.2021.01.122. Epub ahead of print.

Marra AR, Puig-Asensio M, Balkenende E, Livorsi DJ, Goto M, Perencevich EN. Antibiotic use during end-of-life care: A systematic literature review and meta-analysis. Infect Control Hosp Epidemiol. 2021 May;42(5):523-529. doi: 10.1017/ice.2020.1241. Epub 2020 Nov 11.

Rattner M. Increasing our understanding of nonphysical suffering within palliative care: A scoping review. Palliat Support Care. 2021:1-16. doi:10.1017/S1478951521001127.

Thirunavu V, Du R, Wu JY, Berg AT, Lam SK. The role of surgery in the management of Lennox-Gastaut syndrome: A systematic review and meta-analysis of the clinical evidence. Epilepsia. 2021 Apr;62(4):888-907. doi: 10.1111/epi.16851. Epub 2021 Feb 24.

Topoll A, Arnold R. In chronic noncancer illness, palliative care reduces symptoms and health care use but does not improve QoL. Ann Intern Med. 2021 Mar;174(3):JC31. doi: 10.7326/ACPJ202103160-031. Epub 2021 Mar 2.

Vranas KC, Plinke W, Bourne D, Kansagara D, Lee RY, Kross EK, Slatore CG, Sullivan DR. The influence of POLST on treatment intensity at the end of life: A systematic review. J Am Geriatr Soc. 2021 Sep 22. doi: 10.1111/jgs.17447. Epub ahead of print.


Eche IJ, Eche IM, Aronowitz T. An Integrative Review of Factors Associated With Symptom Burden at the End of Life in Children With Cancer. J Pediatr Oncol Nurs. 2020 Mar 10:1043454220909805. doi: 10.1177/1043454220909805. Epub ahead of print.

Greenfield K, Holley S, Schoth DE, Harrop E, Howard RF, Bayliss J, Brook L, Jassal SS, Johnson M, Wong I, Liossi C. A mixed-methods systematic review and meta-analysis of barriers and facilitators to paediatric symptom management at end of life. Palliat Med. 2020 Mar 31:269216320907065. doi: 10.1177/0269216320907065. Epub ahead of print.

Lee YF, Hsu TW, Liang CS, Yeh TC, Chen TY, Chen NC, Chu CS. The Efficacy and Safety of Tube Feeding in Advanced Dementia Patients: A Systemic Review and Meta-Analysis Study. J Am Med Dir Assoc. 2020 Jul 28:S1525-8610(20)30558-2. doi: 10.1016/j.jamda.2020.06.035. Epub ahead of print.

Noorlandt HW, Echteld MA, Tuffrey-Wijne I, Festen DAM, Vrijmoeth C, van der Heide A, Korfage IJ. Shared decision-making with people with intellectual disabilities in the last phase of life: A scoping review. J Intellect Disabil Res. 2020 Sep 11. doi: 10.1111/jir.12774. Epub ahead of print.


Cheng L, Liu F, Feng S, Wang Y, Gu Y, Kang Q. Symptom experience of children with cancer younger than 8 years of age: an integrative review. J Pain Symptom Manage. 2019 Apr 10. pii: S0885-3924(19)30167-8. doi: 10.1016/j.jpainsymman.2019.03.021. [Epub ahead of print]

Ferris A, Price A, Harding K. Pressure ulcers in patients receiving palliative care: A systematic review. Palliat Med. 2019 Apr 24:269216319846023. doi: 10.1177/0269216319846023. [Epub ahead of print]

Hughes JG, Lewith G, MacPherson H, Witt CM, Cummings M, Fisher P. Assessment of the quality of reporting in studies of acupuncture for patients with cancer using the STRICTA guidelines. Acupunct Med. 2019 Jun 12:acupmed2017011592. doi: 10.1136/acupmed-2017-011592. [Epub ahead of print]

Lundby C, Graabaek T, Ryg J, Søndergaard J, Pottegård A, Nielsen D. Health care professionals' attitudes towards deprescribing in older patients with limited life expectancy: a systematic review. Br J Clin Pharmacol. 2019 Jan 10. doi: 10.1111/bcp.13861. [Epub ahead of print]

Murali KM, Mullan J, Roodenrys S, Hassan HC, Lambert K, Lonergan M. Strategies to improve dietary, fluid, dialysis or medication adherence in patients with end stage kidney disease on dialysis: A systematic review and meta-analysis of randomized intervention trials. PLoS One. 2019 Jan 29;14(1):e0211479. doi: 10.1371/journal.pone.0211479. eCollection 2019.

Rowbotham NJ, Palser SC, Smith SJ, Smyth AR. Infection prevention and control in cystic fibrosis: a systematic review of interventions. Expert Rev Respir Med. 2019 Mar 20:1-10. doi: 10.1080/17476348.2019.1595594. [Epub ahead of print]

Ruthirakuhan M, Lanctôt KL, Vieira D, Herrmann N. Natural and Synthetic Cannabinoids for Agitation and Aggression in Alzheimer's Disease: A Meta-Analysis. J Clin Psychiatry. 2019 Jan 29;80(2). pii: 18r12617. doi: 10.4088/JCP.18r12617.


Baker J, Dickman A, Mason S, Ellershaw J. The current evidence base for the feasibility of 48-hour continuous subcutaneous infusions (CSCIs): A systematically-structured review. PLoS One. 2018 Mar 14;13(3):e0194236. doi: 10.1371/journal.pone.0194236. eCollection 2018.

Cheng L, Wang L, He M, Feng S, Zhu Y, Rodgers C. Perspectives of children, family caregivers, and health professionals about pediatric oncology symptoms: a systematic review. Support Care Cancer. 2018 Sep;26(9):2957-2971. doi: 10.1007/s00520-018-4257-3. Epub 2018 May 17.

Huis In Het Veld JG, Verkaik R, van Meijel B, Francke AL. A systematic meta-review of self-management support for people with dementia. Dementia (London). 2018 Jan 1:1471301218772894. doi: 10.1177/1471301218772894. [Epub ahead of print]

Ilha TASH, Comim FV, Copes RM, Compston JE, Premaor MO. HIV and Vertebral Fractures: a Systematic Review and Metanalysis. Sci Rep. 2018 May 18;8(1):7838. doi: 10.1038/s41598-018-26312-9.

Mitchell GK, Senior HE, Johnson CE, Fallon-Ferguson J, Williams B, Monterosso L, Rhee JJ, McVey P, Grant MP, Aubin M, Nwachukwu HT, Yates PM. Systematic review of general practice end-of-life symptom control. BMJ Support Palliat Care. 2018 Jan 20. pii: bmjspcare-2017-001374. doi: 10.1136/bmjspcare-2017-001374. [Epub ahead of print]

Spiegel R, Kalla R, Mantokoudis G, Maire R, Mueller H, Hoerr R, Ihl R. Ginkgo biloba extract EGb 761® alleviates neurosensory symptoms in patients with dementia: a meta-analysis of treatment effects on tinnitus and dizziness in randomized, placebo-controlled trials. Clin Interv Aging. 2018 Jun 13;13:1121-1127. doi: 10.2147/CIA.S157877. eCollection 2018.

Ullgren H, Tsitsi T, Papastavrou E, Charalambous A. How family caregivers of cancer patients manage symptoms at home: A systematic review. Int J Nurs Stud. 2018 May 29;85:68-79. doi: 10.1016/j.ijnurstu.2018.05.004. [Epub ahead of print]

Yu DS, Li PW, Chong SO. Symptom cluster among patients with advanced heart failure: a review of its manifestations and impacts on health outcomes. Curr Opin Support Palliat Care. 2018 Mar;12(1):16-24. doi: 10.1097/SPC.0000000000000316.

Zeng YS, Wang C, Ward KE, Hume AL. Complementary and Alternative Medicine in Hospice and Palliative Care: A Systematic Review. J Pain Symptom Manage. 2018 Nov;56(5):781-794.e4. doi: 10.1016/j.jpainsymman.2018.07.016. Epub 2018 Aug 2.​


Chin-Yee N, Taylor J, Rourke K, Faig D, Davis A, Fergusson D, Saidenberg E. Red blood cell transfusion in adult palliative care: A systematic review. Transfusion. 2017 Dec 1. doi: 10.1111/trf.14413. [Epub ahead of print]

Lebner A, Smith MJ. Deactivating implantable cardioverter-defibrillators (ICDs) in cancer patients: A scoping review of ethical considerations. J Pain Manage. 2017;10(1):99-106. [No Abstract Available].

Montgomery GH, Sucala M, Baum T, Schnur JB. Hypnosis for symptom control in cancer patients at the end-of-life: A systematic review. Int J Clin Exp Hypn. 2017 Jul-Sep;65(3):296-307. doi: 10.1080/00207144.2017.1314728.

Moradian S, Voelker N, Brown C, Liu G, Howell D. Effectiveness of Internet-based interventions in managing chemotherapy-related symptoms in patients with cancer: a systematic literature review. Support Care Cancer. 2017 Sep 25. doi: 10.1007/s00520-017-3900-8. [Epub ahead of print]

Zhou H, Wu W, Tang X, Zhou J, Shen Y. Effect of hyperthermic intrathoracic chemotherapy (HITHOC) on the malignant pleural effusion: A systematic review and meta-analysis. Medicine (Baltimore). 2017 Jan;96(1):e5532.


Ramsenthaler C, Kane P, Gao W, Siegert RJ, Edmonds PM, Schey SA, Higginson IJ. Prevalence of symptoms in patients with multiple myeloma: a systematic review and meta-analysis. Eur J Haematol. 2016 Nov;97(5):416-429. Epub 2016 Sep 6.

Xiao W, Chow KM, So WK, Leung DY, Chan CW. The Effectiveness of Psychoeducational Intervention on Managing Symptom Clusters in Patients With Cancer: A Systematic Review of Randomized Controlled Trials. Cancer Nurs. 2016 Jul-Aug;39(4):279-91.


Aktas A, Walsh D, Kirkova J. The psychometric properties of cancer multisymptom assessment instruments: a clinical review. Support Care Cancer. 2015 Jul;23(7):2189-202.Epub 2015 Apr 19.

Kwekkeboom KL, Bratzke LC. A Systematic Review of Relaxation, Meditation, and Guided Imagery Strategies for Symptom Management in Heart Failure. J Cardiovasc Nurs. 2015 Jun 10.

Mummadi S, Kumbam A, Hahn PY. Malignant pleural effusions and the role of talc poudrage and talc slurry: a systematic review and meta-analysis. Version 2. F1000Res. 2014 Oct 27 [revised 2015 Feb 17];3:254. doi: 10.12688/f1000research.5538.2. eCollection 2014.

Sakkas GK Giannaki CD, Karatzaferi C, Maridaki M, Koutedakis Y, Hadjigeorgiou GM, Stefanidis I. Current trends in the management of uremic restless legs syndrome: a systematic review on aspects related to quality of life, cardiovascular mortality and survival. Sleep Med Rev. 2015 Jun;21:39-49. Epub 2014 Aug 15.


Coolbrandt A, Wildiers H, Aertgeerts B, Van der Elst E, Laenen A, Dierckx de Casterlé B, van Achterberg T, Milisen K. Characteristics and effectiveness of complex nursing interventions aimed at reducing symptom burden in adult patients treated with chemotherapy: a systematic review of randomized controlled trials. Int J Nurs Stud. 2014 Mar;51(3):495-510. doi: 10.1016/j.ijnurstu.2013.08.008. Epub 2013 Sep 4.

Dong ST, Butow PN, Costa DS, Lovell MR, Aga M. Symptom Clusters in Patients With Advanced Cancer: A Systematic Review of Observational Studies. J Pain Symptom Manage. 2014 Apr 2. [Epub ahead of print]

Koekkoek JAF, Dirven L, Reijneveld JC, Postma TJ, Grant R, Pace A, Oberndorfer S, Heimans JJ, Taphoorn MJ. Epilepsy in the end of life phase of brain tumor patients: a systematic review. Neurooncol Pract. 2014 Sep 1;1(3):134-40.

Lewis KB, Stacey D, Matlock DD. Making decisions about implantable cardioverter-defibrillators from implantation to end of life: an integrative review of patients' perspectives. Patient. 2014;7(3):243-60.

Moens K, Higginson IJ, Harding R; EURO IMPACT; EURO IMPACT. Are There Differences in the Prevalence of Palliative Care-Related Problems in People Living With Advanced Cancer and Eight Non-Cancer Conditions? A Systematic Review. J Pain Symptom Manage. 2014 Oct;48(4):660-677. Epub 2014 May 5.

Tong A, Cheung KL, Nair SS, Kurella Tamura M, Craig JC, Winkelmayer WC. Thematic synthesis of qualitative studies on patient and caregiver perspectives on end-of-life care in CKD. Am J Kidney Dis. 2014 Jun;63(6):913-27.Epub 2014 Jan 7.

Uceda Torres ME, Rodríguez Rodríguez JN, Sánchez Ramos JL, Alvarado Gómez F. Transfusion in palliative cancer patients: a review of the literature. J Palliat Med. 2014 Jan;17(1):88-104. Epub 2013 Dec 10.

Van Lancker A, Velghe A, Van Hecke A, Verbrugghe M, Van Den Noortgate N, Grypdonck M, Verhaeghe S, Bekkering G, Beeckman D. Prevalence of symptoms in older cancer patients receiving palliative care: a systematic review and meta-analysis. J Pain Symptom Manage. 2014 Jan;47(1):90-104. Epub 2013 Jun 10.


Oldenmenger WH, de Raaf PJ, de Klerk C, van der Rijt CC. Cut points on 0-10 numeric rating scales for symptoms included in the edmonton symptom assessment scale in cancer patients: a systematic review. J Pain Symptom Manage. 2013 Jun;45(6):1083-93.

Rosenberg JH, Albrecht JS, Fromme EK, Noble BN, McGregor JC, Comer AC, Furuno JP. Antimicrobial use for symptom management in patients receiving hospice and palliative care: a systematic review. J Palliat Med. 2013 Dec;16(12):1568-74.Epub 2013 Oct 23.


Amarasuriya UK, Myles PR, Sanders RD. Long-term benzodiazepine use and mortality: are we doing the right studies? Curr Drug Saf. 2012 Nov 1;7(5):367-71.

Gamper EM, Zabernigg A, Wintner LM, Giesinger JM, Oberguggenberger A, Kemmler G, Sperner-Unterweger B, Holzner B. Coming to your senses: detecting taste and smell alterations in chemotherapy patients. A systematic review. J Pain Symptom Manage. 2012 Dec;44(6):880-95. Epub 2012 Aug 24.

Thavarajah N, Chen E, Zeng L, Bedard G, Di Giovanni J, Lemke M, Lauzon N, Zhou M, Chu D, Chow E. Symptom clusters in patients with metastatic cancer: a literature review. Expert Rev Pharmacoecon Outcomes Res. 2012 Oct;12(5):597-604.

Trajkovic-Vidakovic M, de Graeff A, Voest EE, Teunissen SC. Symptoms tell it all: a systematic review of the value of symptom assessment to predict survival in advanced cancer patients. Crit Rev Oncol Hematol. 2012 Oct;84(1):130-48. doi: 10.1016/j.critrevonc.2012.02.011. Epub 2012 Mar 31.


Chew C, Craig L, Edwards R, Moss J, O'Dwyer PJ. Safety and efficacy of percutaneous vertebroplasty in malignancy: a systematic review. Clin Radiol. 2011 Jan;66(1):63-72. Epub 2010 Nov 16.

Gilbertson-White S, Aouizerat BE, Jahan T, Miaskowski C. A review of the literature on multiple symptoms, their predictors, and associated outcomes in patients with advanced cancer. Palliat Support Care. 2011 Mar;9(1):81-102.

Kaplan M, Mahon S, Cope D, Keating E, Hill S, Jacobson M. Putting evidence into practice: evidence-based interventions for hot flashes resulting from cancer therapies. Clin J Oncol Nurs. 2011 Apr;15(2):149-57.

Kirkova J, Aktas A, Walsh D, Davis MP. Cancer symptom clusters: clinical and research methodology.J Palliat Med. 2011 Oct;14(10):1149-66. Epub 2011 Aug 23.

Lee YH, Chiou PY, Chang PH, Hayter M. A systematic review of the effectiveness of problem-solving approaches towards symptom management in cancer care. J Clin Nurs. 2011 Jan;20(1-2):73-85. doi: 10.1111/j.1365-2702.2010.03401.x. Epub 2010 Nov 2.

Redelmeier DA, Dickinson VM. Determining whether a patient is feeling better: pitfalls from the science of human perception. J Gen Intern Med. 2011 Aug;26(8):900-6.Epub 2011 Feb 19.


Askoxylakis V, Thieke C, Pleger ST, Most P, Tanner J, Lindel K, Katus HA, Debus J, Bischof M. Long-term survival of cancer patients compared to heart failure and stroke: a systematic review. BMC Cancer. 2010 Mar 22;10:105.

Green AJ, De-Vries K. Cannabis use in palliative care--An examination of the evidence and the implications for nurses. J Clin Nurs. 2010;19(17-18):2454–62.

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Last updated 10 January 2024