Review collection - Respiratory secretions 

9 reviews
See also: Last days of life, Resuscitation, Dyspnoea


Taburee W, Dhippayom T, Nagaviroj K, Dilokthornsakul P. Effects of Anticholinergics on Death Rattle: A Systematic Review and Network Meta-Analysis. J Palliat Med. 2023 Mar;26(3):431-440. doi: 10.1089/jpm.2022.0386. Epub 2022 Oct 3.


Jansen K, Haugen DF, Pont L, Ruths S. Safety and Effectiveness of Palliative Drug Treatment in the Last Days of Life-A Systematic Literature Review. J Pain Symptom Manage. 2018 Feb;55(2):508-521.e3. doi: 10.1016/j.jpainsymman.2017.06.010. Epub 2017 Aug 10.

Kolb H, Snowden A, Stevens E. Systematic Review and Narrative Summary: Treatments for and Risk Factors Associated with Respiratory Tract Secretions (Death Rattle) in the Dying Adult. J Adv Nurs. 2018 Mar 1. doi: 10.1111/jan.13557. [Epub ahead of print]


Arcuri JF, Abarshi E, Preston NJ, Brine J, Pires Di Lorenzo VA. Benefits of interventions for respiratory secretion management in adult palliative care patients-a systematic review. BMC Palliat Care. 2016 Aug 9;15:74.

Rémi C, Rémi J, Bausewein C. Pharmacological Management of Bronchorrhea in Malignant Disease: A Systematic Literature Review. J Pain Symptom Manage. 2016 May;51(5):916-25. Epub 2016 Mar 12.


Kintzel PE, Chase SL, Thomas W, Vancamp DM, Clements EA. Anticholinergic medications for managing noisy respirations in adult hospice patients. Am J Health Syst Pharm. 2009 Mar 1;66(5):458-64.


Wee B, Hillier R. Interventions for noisy breathing in patients near to death. Cochrane Database Syst Rev. 2008 Jan 23;(1):CD005177.


Lawrey H. Hyoscine vs glycopyrronium for drying respiratory secretions in dying patients. Br J Community Nurs. 2005 Sep;10(9):421-6.


Bennett M, Lucas V, Brennan M, Hughes A, O’Donnell, Wee B; Association for Palliative Medicine's Science Committee. Using anti-muscarinic drugs in the management of death rattle: evidence based guidelines for palliative care. Palliat Med. 2002 Sep;16(5):369-74.

Last updated 05 April 2023