Review collection - Palliative radiotherapy 

90 reviews


Kamel R, Dennis K, Doody J, Pantarotto J. Ablative vs. Non-Ablative Radiotherapy in Palliating Locally Advanced Pancreatic Cancer: A Single Institution Experience and a Systematic Review of the Literature. Cancers (Basel). 2023 Jun 1;15(11):3016. doi: 10.3390/cancers15113016.

Khanmohammadi S, Noroozi A, Yekaninejad MS, Rezaei N. Cryoablation for the Palliation of Painful Bone Metastasis: A Systematic Review. Cardiovasc Intervent Radiol. 2023 Jan 11. doi: 10.1007/s00270-022-03356-z. Epub ahead of print.

Mercadante S. Breakthrough cancer pain in the radiotherapy setting: a systematic and critical review. Expert Rev Anticancer Ther. 2023 Mar;23(3):229-234. doi: 10.1080/14737140.2023.2182773. Epub 2023 Feb 23.

Pezzulla D, Di Franco R, Zamagni A, Pastore F, Longo S, Dominici L, et al. Radiotherapy of orbital metastases: A systematic review of management and treatment outcomes on behalf of palliative care study group of Italian association of radiotherapy and clinical oncology (AIRO). Br J Radiol. 2023 Nov;96(1151):20230124.

Song J, Brown C, Dennis K, Gaudet M, Haddad A. Palliative Radiotherapy for Haemostasis in Malignancy: a Systematic Review. Clin Oncol (R Coll Radiol). 2023 Jun 10:S0936-6555(23)00220-0. doi: 10.1016/j.clon.2023.06.007. Epub ahead of print.

Viani GA, Gouveia AG, Matsuura FK, Neves LVF, Marta GN, Chua MLK, Moraes YF. Assessing the efficacy of palliative radiation treatment schemes for locally advanced squamous cell carcinoma of the head and neck: a meta-analysis. Rep Pract Oncol Radiother. 2023 Jun 26;28(2):137-146. doi: 10.5603/RPOR.a2023.0021.

Zhou D, Zhao N, Xu H, Zheng Y, Ming P, Jiang Z, Ge W, Cao D. The safety and efficacy of immunotherapy and palliative radiotherapy in patients with metastatic non-small cell lung cancer: a systematic review and meta-analysis of 13 prospective studies. Expert Rev Anticancer Ther. 2023 Jul;23(7):761-773. doi: 10.1080/14737140.2023.2219454. Epub 2023 Jun 5.


Chand CP, Greenley S, Macleod U, Lind M, Barton R, Kelly C. Geographical distance and reduced access to palliative radiotherapy: systematic review and meta-analysis. BMJ Support Palliat Care. 2022 Mar 15:bmjspcare-2021-003356. doi: 10.1136/bmjspcare-2021-003356. Epub ahead of print.

Fabian A, Domschikowski J, Letsch A, Schmalz C, Freitag-Wolf S, Dunst J, Krug D. Clinical Endpoints in Trials of Palliative Radiotherapy: a Systematic Meta-Research Analysis. Radiother Oncol. 2022 Jul 19:S0167-8140(22)04209-8. doi: 10.1016/j.radonc.2022.07.013. Epub ahead of print.

Giammalva GR, Ferini G, Torregrossa F, Brunasso L, Musso S, Benigno UE, Gerardi RM, Bonosi L, Costanzo R, Paolini F, Palmisciano P, Umana GE, Di Bonaventura R, Sturiale CL, Iacopino DG, Maugeri R. The Palliative Care in the Metastatic Spinal Tumors. A Systematic Review on the Radiotherapy and Surgical Perspective. Life (Basel). 2022 Apr 12;12(4):571. doi: 10.3390/life12040571.

Kutzko JH, Dadwal P, Holt T, Rahman MA, Zahir SF, Hickey B. Defining the expected 30-day mortality for patients undergoing palliative radiotherapy: A meta-analysis. Radiother Oncol. 2022 Jan 29;168:147-210. doi: 10.1016/j.radonc.2022.01.030. Epub ahead of print.

Song S, Gong S, Lei T, Tian H, Lu T, Lei C, Jin H, Yang W, Yang K, Guo T.
Comparative efficacy and safety of local palliative therapeutics for unresectable malignant biliary obstruction: a Bayesian network meta-analysis. Expert Rev Gastroenterol Hepatol. 2022 Jun;16(6):555-567. doi: 10.1080/17474124.2022.2085090. Epub 2022 Jun 14.

Song S, Jin H, Cheng Q, Gong S, Lv K, Lei T, Tian H, Li X, Lei C, Yang W, Yang K, Guo T. Local palliative therapies for unresectable malignant biliary obstruction: radiofrequency ablation combined with stent or biliary stent alone? An updated meta-analysis of nineteen trials. Surg Endosc. 2022 Mar 16. doi: 10.1007/s00464-022-09181-2. Epub ahead of print.

Vornhülz M, Anton S, Eross B, Szakács Z, Hegyi P, Regel I, Belka C, Niyazi M, Mayerle J, Beyer G. Role of stereotactic body radiation in the enhancement of the quality of life in locally advanced pancreatic adenocarcinoma: a systematic review. Radiat Oncol. 2022 Jun 17;17(1):108. doi: 10.1186/s13014-022-02076-5.


Bravo-Soto GA, Brañes R, Peña J, Nervi B. Palliative chemotherapy for advanced gallbladder cancer. Medwave. 2021 Apr 9;21(3):e8045. Spanish, English. doi: 10.5867/medwave.2021.03.8046.

Desideri I, Becherini C, Belgioia L, Merlotti A, Ciccone LP, Franzese C, Loi M, De Felice F, Mazzola R, Caini S, Livi L, Bonomo P. Palliative radiotherapy in older adults with head and neck squamous cell carcinoma: A systematic review. Oral Oncol. 2021 May 24;119:105355. doi: 10.1016/j.oraloncology.2021.105355. Epub ahead of print.

Fabian A, Domschikowski J, Hoffmann M, Weiner O, Schmalz C, Dunst J, Krug D. Patient-Reported Outcomes Assessing the Impact of Palliative Radiotherapy on Quality of Life and Symptom Burden in Head and Neck Cancer Patients: A Systematic Review. Front Oncol. 2021 Jun 4;11:683042. doi: 10.3389/fonc.2021.683042.

Pobar I, Job M, Holt T, Hargrave C, Hickey B. Prognostic tools for survival prediction in advanced cancer patients: A systematic review. J Med Imaging Radiat Oncol. 2021 May 10. doi: 10.1111/1754-9485.13185. Epub ahead of print.


Lo Presti G, Roncador M, Biggiogero M, Soloni C, Franzetti-Pellanda A. Radiation oncologists role, training and perceptions in palliative care: a systematic review. Rep Pract Oncol Radiother. 2020 Nov-Dec;25(6):939-942. doi: 10.1016/j.rpor.2020.09.007. Epub 2020 Oct 1.

Oldenburger E, Oldenburger F, Coolbrandt A, Isebaert S, Neyens I, Sevenants A, Van Audenhove C, Haustermans K. The use of patient reported outcome measures (PROMs) in palliative radiotherapy: A topical review. Radiother Oncol. 2020 Apr 29;149:94-103. doi: 10.1016/j.radonc.2020.04.045. Epub ahead of print.


Lancellotta V, Cellini F, Fionda B, De Sanctis V, Vidali C, Fusco V, Barbera F, Gambacorta MA, Corvò R, Magrini SM, Tagliaferri L. The role of palliative interventional radiotherapy (brachytherapy) in esophageal cancer: An AIRO (Italian Association of Radiotherapy and Clinical Oncology) systematic review focused on dysphagia-free survival. Brachytherapy. 2019 Oct 18. pii: S1538-4721(19)30583-5. doi: 10.1016/j.brachy.2019.09.005. [Epub ahead of print]

Livergant J, Howard M, Klein J. Barriers to Referral for Palliative Radiotherapy by Physicians: A Systematic Review. Clin Oncol (R Coll Radiol). 2019 Jan;31(1):e75-e84. doi: 10.1016/j.clon.2018.09.009. Epub 2018 Oct 21.


Pin Y, Paix A, Le Fèvre C, Antoni D, Blondet C, Noël G. A systematic review of palliative bone radiotherapy based on pain relief and retreatment rates. Crit Rev Oncol Hematol. 2018 Mar;123:132-137. doi: 10.1016/j.critrevonc.2018.01.006. Epub 2018 Jan 31.

Razvi Y, Chan S, Zaki P, McKenzie E, Lam H, Van Der Velden JM, Alqaderi A, Silva MF, Chow E. Predicting survival of patients treated with palliative radiotherapy: a systematic review. Expert Rev Qual Life Cancer Care. 2018 Jul 10;3(4):105-111.

Rich SE, Chow R, Raman S, Liang Zeng K, Lutz S, Lam H, Silva MF, Chow E. Update of the systematic review of palliative radiation therapy fractionation for bone metastases. Radiother Oncol. 2018 Mar;126(3):547-557. doi: 10.1016/j.radonc.2018.01.003. Epub 2018 Feb 1.

Wang SJ, Hathout L, Malhotra U, Maloney-Patel N, Kilic S, Poplin E, Jabbour SK. Decision-Making Strategy for Rectal Cancer Management Using Radiation Therapy for Elderly or Comorbid Patients. Int J Radiat Oncol Biol Phys. 2018 Mar 15;100(4):926-944. doi: 10.1016/j.ijrobp.2017.12.261.


Chow R, Hoskin P, Chan S, Mesci A, Hollenberg D, Lam H, DeAngelis C, Chow E. Efficacy of multiple fraction conventional radiation therapy for painful uncomplicated bone metastases: A systematic review. Radiother Oncol. 2017 Mar;122(3):323-331. doi: 10.1016/j.radonc.2016.12.031. Epub 2017 Jan 12.

Fuccio L, Mandolesi D, Farioli A, Hassan C, Frazzoni L, Guido A, de Bortoli N, Cilla S, Pierantoni C, Violante FS, Bazzoli F, Repici A, Morganti AG. Brachytherapy for the palliation of dysphagia owing to esophageal cancer: A systematic review and meta-analysis of prospective studies. Radiother Oncol. 2017 Mar;122(3):332-339. doi: 10.1016/j.radonc.2016.12.034. Epub 2017 Jan 16.

Park KR, Lee CG, Tseng YD, Liao JJ, Reddy S, Bruera E, Yennurajalingam S. Palliative radiation therapy in the last 30 days of life: A systematic review. Radiother Oncol. 2017 Oct 16. pii: S0167-8140(17)32583-5. doi: 10.1016/j.radonc.2017.09.016. [Epub ahead of print]

Ruhlmann CH, Jahn F, Jordan K, Dennis K, Maranzano E, Molassiotis A, Roila F, Feyer P. 2016 updated MASCC/ESMO consensus recommendations: prevention of radiotherapy-induced nausea and vomiting. Support Care Cancer. 2017 Jan;25(1):309-316. Epub 2016 Sep 13.

Sun L, Zhao F, Zeng Y, Yi C. Risks and benefits of multimodal esophageal cancer treatments: A meta-analysis. Med Sci Monit. 2017 Feb 19;23:889-910.

Youroukou A, Gkiozos I, Kalaitzi Z, Tsalafoutas I, Papalla K, Charpidou A, Kouloulias V. The potential role of brachytherapy in the irradiation of patients with lung cancer: a systematic review. Clin Transl Oncol. 2017 Aug;19(8):945-950. doi: 10.1007/s12094-017-1635-0. Epub 2017 Mar 2.


Davies AN, Thompson J. Parasympathomimetic drugs for the treatment of salivary gland dysfunction due to radiotherapy. Cochrane Database Syst Rev. 2015 Oct 5;10:CD003782.

Eleje GU, Eke AC, Igberase GO, Igwegbe AO, Eleje LI. Palliative interventions for controlling vaginal bleeding in advanced cervical cancer. Cochrane Database Syst Rev. 2015 May 1;5:CD011000. doi: 10.1002/14651858.CD011000.pub2.

Fu G, Agarwal A, Popovic M, Lam M, Milakovic M, Fu W, Cheon S, DiGiovanni J, Chow R, Fu T, Lam H, Lechner B, Pulenzas N, Chow E. Survival benefit from palliative treatment in patients with advanced prostate cancer: A selected review. J Pain Manage. 2015;8(4):313-320. [No Abstract Available].

Kothari G, Foroudi F, Gill S, Corcoran NM, Siva S. Outcomes of stereotactic radiotherapy for cranial and extracranial metastatic renal cell carcinoma: a systematic review. Acta Oncol. 2015 Feb;54(2):148-57. Epub 2014 Aug 20.

McDonald R, Chow E, Rowbottom L, Bedard G, Lam H, Wong E, Popovic M, Pulenzas N, Tsao M. Quality of life after palliative radiotherapy in bone metastases: A literature review. J Bone Oncol. 2015 Mar;4(1):24-31.

Stevens R, Macbeth F, Toy E, Coles B, Lester JF. Palliative radiotherapy regimens for patients with thoracic symptoms from non-small cell lung cancer. Cochrane Database Syst Rev. 2015 Jan 14;1:CD002143. CD002143.pub4.


Cameron MG, Kersten C, Guren MG, Fosså SD, Vistad I. Palliative pelvic radiotherapy of symptomatic incurable prostate cancer - a systematic review. Radiother Oncol. 2014 Jan;110(1):55-60. Epub 2013 Sep 14.

Ma JT, Zheng JH, Han CB, Guo QY. Meta-analysis comparing higher and lower dose radiotherapy for palliation in locally advanced lung cancer. Cancer Sci. 2014 Aug;105(8):1015-22.

McDonald R, Chow E, Lam H, Rowbottom L, Soliman H. International patterns of practice in radiotherapy for bone metastases: A review of the literature. J Bone Oncol. 2014 Nov;3(3-4):96-102.

Pang X, Wei W, Leng W, Chen Q, Xia H, Chen L, Li R. Radiotherapy for gastric cancer: a systematic review and meta-analysis. Tumour Biol. 2014 Jan;35(1):387-96. Epub 2013 Aug 9.

Popovic M, den Hartogh M, Zhang L, Poon M, Lam H, Bedard G, Pulenzas N, Lechner B, Chow E. Review of international patterns of practice for the treatment of painful bone metastases with palliative radiotherapy from 1993 to 2013. Radiother Oncol. 2014 Apr;111(1):11-7.Epub 2014 Feb 20.

Waller A, Forshaw K, Bryant J, Mair S. Interventions for preparing patients for chemotherapy and radiotherapy: a systematic review. Support Care Cancer. 2014 Aug;22(8):2297-308.Epub 2014 Jun 7.

Wong E, Hoskin P, Bedard G, Poon M, Zeng L, Lam H, Vulpe H, Tsao M, Pulenzas N, Chow E. Re-irradiation for painful bone metastases - a systematic review. Radiother Oncol. 2014 Jan;110(1):61-70. Epub 2013 Oct 3.


Amdal CD, Jacobsen AB, Guren MG, Bjordal K. Patient-reported outcomes evaluating palliative radiotherapy and chemotherapy in patients with oesophageal cancer: a systematic review. Acta Oncol. 2013 May;52(4):679-90. Epub 2012 Nov 28.

Dennis K, Makhani L, Zeng L, Lam H, Chow E. Single fraction conventional external beam radiation therapy for bone metastases: a systematic review of randomised controlled trials. Radiother Oncol. 2013 Jan;106(1):5-14.

Saylor PJ, Armstrong AJ, Fizazi K, Freedland S, Saad F, Smith MR, Tombal B, Pienta K. New and emerging therapies for bone metastases in genitourinary cancers. Eur Urol. 2013 Feb;63(2):309-20.Epub 2012 Nov 23


Chow E, Zeng L, Salvo N, Dennis K, Tsao M, Lutz S. Update on the systematic review of palliative radiotherapy trials for bone metastases. Clin Oncol (R Coll Radiol). 2012 Mar;24(2):112-24. Epub 2011 Nov 29.

Christensen MH, Petersen LJ. Radionuclide treatment of painful bone metastases in patients with breast cancer: a systematic review. Cancer Treat Rev. 2012 Apr;38(2):164-71.

Gillan C, Briggs K, Pazos AG, Maurus M, Harnett N, Catton P, Wiljer D. Barriers to accessing radiation therapy in Canada: a systematic review. Radiat Oncol. 2012 Oct 12;7:167.

Rodrigues G, Macbeth F, Burmeister B, Kelly KL, Bezjak A, Langer C, Hahn C, Movsas B. Consensus statement on palliative lung radiotherapy: third international consensus workshop on palliative radiotherapy and symptom control. Clin Lung Cancer. 2012 Jan;13(1):1-5.

Reveiz L1, Rueda JR, Cardona AF. Palliative endobronchial brachytherapy for non-small cell lung cancer. Cochrane Database Syst Rev. 2012 Dec 12;12:CD004284.

Trilling GM, Cho H, Ugas MA, Saeed S, Katunda A, Jerjes W, Giannoudis P. Spinal metastasis in head and neck cancer. Head Neck Oncol. 2012 Jun 20;4:36.


Bjordal JM, Bensadoun RJ, Tunèr J, Frigo L, Gjerde K, Lopes-Martins RA. A systematic review with meta-analysis of the effect of low-level laser therapy (LLLT) in cancer therapy-induced oral mucositis. Support Care Cancer. 2011 Aug;19(8):1069-77. Epub 2011 Jun 10.

Lutz S, Berk L, Chang E, Chow E, Hahn C, Hoskin P, Howell D, Konski A, Kachnic L, Lo S, Sahgal A, Silverman L, von Gunten C, Mendel E, Vassil A, Bruner DW, Hartsell W; American Society for Radiation Oncology (ASTRO). Palliative radiotherapy for bone metastases: an ASTRO evidence-based guideline. Int J Radiat Oncol Biol Phys. 2011 Mar 15;79(4):965-76. Epub 2011 Jan 27.

van Lonkhuijzen L, Thomas G. Palliative radiotherapy for cervical carcinoma, a systematic review. Radiother Oncol. 2011 Mar;98(3):287-91.


Alberta Health Services, Cancer Care. Palliative radiotherapy. Edmonton (Alberta): Alberta Health Services, Cancer Care; 2010 Jul. 20 p. (Clinical practice guideline; no. PAL-001). [No abstract available]

Bensadoun RJ, Riesenbeck D, Lockhart PB, Elting LS, Spijkervet FK, Brennan MT; Trismus Section, Oral Care Study Group, Multinational Association for Supportive Care in Cancer (MASCC)/International Society of Oral Oncology (ISOO). A systematic review of trismus induced by cancer therapies in head and neck cancer patients. Support Care Cancer. 2010 Aug;18(8):1033-8. Epub 2010 Mar 6.

Dy SM. Evidence-based approaches to pain in advanced cancer. Cancer J. 2010 Sep-Oct;16(5):500-6.

Hovan AJ, Williams PM, Stevenson-Moore P, Wahlin YB, Ohrn KE, Elting LS, Spijkervet FK, Brennan MT;Dysgeusia Section, Oral Care Study Group, Multinational Association of Supportive Care in Cancer (MASCC)/International Society of Oral Oncology (ISOO). A systematic review of dysgeusia induced by cancer therapies. Support Care Cancer. 2010 Aug;18(8):1081-7. Epub 2010 May 22.

Jensen SB, Pedersen AM, Vissink A, Andersen E, Brown CG, Davies AN, Dutilh J, Fulton JS, Jankovic L, Lopes NN, Mello AL, Muniz LV, Murdoch-Kinch CA, Nair RG, Napeñas JJ, Nogueira-Rodrigues A, Saunders D, Stirling B, von Bültzingslöwen I, Weikel DS, Elting LS, Spijkervet FK, Brennan MT; Salivary Gland Hypofunction/Xerostomia Section, Oral Care Study Group, Multinational Association of Supportive Care in Cancer (MASCC)/International Society of Oral Oncology (ISOO). A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies: prevalence, severity and impact on quality of life. Support Care Cancer. 2010 Aug;18(8):1039-60. Epub 2010 Mar 17.

Jensen SB, Pedersen AM, Vissink A, Andersen E, Brown CG, Davies AN, Dutilh J, Fulton JS, Jankovic L, Lopes NN, Mello AL, Muniz LV, Murdoch-Kinch CA, Nair RG, Napeñas JJ, Nogueira-Rodrigues A, Saunders D, Stirling B, von Bültzingslöwen I, Weikel DS, Elting LS, Spijkervet FK, Brennan MT; Salivary Gland Hypofunction/Xerostomia Section; Oral Care Study Group; Multinational Association of Supportive Care in Cancer (MASCC)/International Society of Oral Oncology (ISOO). A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies: management strategies and economic impact. Support Care Cancer. 2010 Aug;18(8):1061-79. Epub 2010 Mar 25.

O'Sullivan EM, Higginson IJ. Clinical effectiveness and safety of acupuncture in the treatment of irradiation-induced xerostomia in patients with head and neck cancer: a systematic review. Acupunct Med. 2010 Dec;28(4):191-9. Epub 2010 Nov 9.


Bird J, Hayter M. A review of the literature on the impact of renal cancer therapy on quality of life. J Clin Nurs. 2009 Oct;18(20):2783-800.

Salvo N, Hadi S, Napolskikh J, Goh P, Sinclair E, Chow E. Quality of life measurement in cancer patients receiving palliative radiotherapy for symptomatic lung cancer: a literature review. Curr Oncol. 2009 Mar;16(2):16-28.

Sohl SJ, Schnur JB, Montgomery GH. A meta-analysis of the relationship between response expectancies and cancer treatment-related side effects. J Pain Symptom Manage. 2009 Nov;38(5):775-84. Epub 2009 Sep 23.

Stone CA, O'Leary N. Systematic review of the effectiveness of botulinum toxin or radiotherapy for sialorrhea in patients with amyotrophic lateral sclerosis. J Pain Symptom Manage. 2009 Feb;37(2):246-58.


Bomeli SR, Desai SC, Johnson JT, Walvekar RR. Management of salivary flow in head and neck cancer patients--a systematic review. Oral Oncol. 2008 Nov;44(11):1000-8. Epub 2008 May 16.

George R, Jeba J, Ramkumar G, Chacko AG, Leng M, Tharyan P. Interventions for the treatment of metastatic extradural spinal cord compression in adults. Cochrane Database Syst Rev. 2008 Oct 8;(4):CD006716.

Isenring I, Hill J, Davidson W, Brown T, Baumgartner L, Kaegi K, Reeves M, Ash S, Thomas S, McPhee N, Bauer J. Evidence based practice guidelines for the nutritional management of patients receiving radiation therapy. Nutr Diet. 2008 Mar;65(Suppl. 1):S1-S20. (No Abstract)

Li KK, Hadi S, Kirou-Mauro A, Chow E. When should we define the response rates in the treatment of bone metastases by palliative radiotherapy? Clin Oncol (R Coll Radiol). 2008 Feb;20(1):83-9. Epub 2007 Nov 5.

Wong J, Hird A, Kirou-Mauro A, Napolskikh J, Chow E. Quality of life in brain metastases radiation trials: a literature review. Curr Oncol. 2008 Oct;15(5):25-45.


Chow E, Harris K, Fan G, Tsao M, Sze WM. Palliative radiotherapy trials for bone metastases: a systematic review. J Clin Oncol. 2007 Apr 10;25(11):1423-36.

Clarkson JE, Worthington HV, Eden OB. Interventions for treating oral mucositis for patients with cancer receiving treatment. Cochrane Database Syst Rev. 2007 Apr 18;(2):CD001973.


Dennert G, Horneber M. Selenium for alleviating the side effects of chemotherapy, radiotherapy and surgery in cancer patients. Cochrane Database Syst Rev. 2006 Jul 19;3:CD005037.

Lester JF, Macbeth FR, Toy E, Coles B. Palliative radiotherapy regimens for non-small cell lung cancer. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD002143.

Sasse AD, Clark LG, Sasse EC, Clark OA. Amifostine reduces side effects and improves complete response rate during radiotherapy: results of a meta-analysis. Int J Radiat Oncol Biol Phys. 2006 Mar 1;64(3):784-91. Epub 2005 Sep 29.


Bauman G, Charette M, Reid R, Sathya J. Radiopharmaceuticals for the palliation of painful bone metastasis-a systemic review. Radiother Oncol. 2005 Jun;75(3):258-70.

McKee L. Palliative radiotherapy for painful bone metastases, single versus multiple fraction treatment: a literature review. Can J Med Radiat Tech. 2005 Autumn;36(3):7-16.

Richardson J, Smith JE, McIntyre M, Thomas R, Pilkington K. Aloe vera for preventing radiation-induced skin reactions: a systematic literature review. Clin Oncol (R Coll Radiol). 2005 Sep;17(6):478-84.

Shakespeare TP, Thiagarajan A, Gebski V. Evaluation of the quality of radiotherapy randomized trials for painful bone metastases. Cancer. 2005 May 1;103(9):1976-81.


Falkmer U, Jarhult J, Wersall P, Cavallin-Stahl E. A systematic overview of radiation therapy effects in skeletal metastases. Acta Oncol. 2003;42(5-6):620-33.

Klimo P Jr., Kestle JR, Schmidt MH. Treatment of metastatic spinal epidural disease: a review of the literature. Neurosurg Focus. 2003 Nov 15;15(5):E1.

Lindholm C, Cavallin-Stahl E, Ceberg J, Frodin JE, Littbrand B, Moller TR; SBU Survey Group. Radiotherapy practices in Sweden compared to the scientific evidence. Acta Oncol. 2003;42(5-6):416-29.

Toy E, Macbeth F, Coles B, Melville A, Eastwood A. Palliative thoracic radiotherapy for non-small-cell lung cancer: a systematic review. Am J Clin Oncol. 2003 Apr;26(2):112-20.


Sze WM, Shelley M, Held I, Mason M. Palliation of metastatic bone pain: single fraction versus multifraction radiotherapy - a systematic review of the randomised trials. Cochrane Database Syst Rev. 2002(1):CD004721.

Wu JS, Bezjak A, Chow E, Kirkbride P. Primary treatment endpoint following palliative radiotherapy for painful bone metastases: need for a consensus definition. Clin Oncol (R Coll Radiol). 2002 Feb;14(1):70-7.


Dawson R, Currow D, Stevens G, Morgan G, Barton MB. Radiotherapy for bone metastases: a critical appraisal of outcome measures. J Pain Symptom Manage. 1999 Mar;17(3):208-18.

McQuay HJ, Collins SL, Carroll D, Moore RA. Radiotherapy for the palliation of painful bone metastases. Cochrane Database Syst Rev. 1999;(3):CD001793. [Withdrawn 2013]


McQuay HJ, Carroll D, Moore RA. Radiotherapy for painful bone metastases: a systematic review. Clin Oncol. 1997;9(3):150-4.

Last updated 01 November 2023