Review collection - Fluids and hydration

25 reviews
See also: Last days of life, Nutrition


Buchan EJ, Haywood A, Syrmis W, Good P. Medically assisted hydration for adults receiving palliative care. Cochrane Database Syst Rev. 2023;12(12):Cd006273.

Hammond L, Chakraborty A, Thorpe C, O'Loughlin M, Allcroft P, Phelan C. Relieving Perception of Thirst and Xerostomia in Patients with Palliative and End-of-life Care Needs: A Rapid Review. J Pain Symptom Manage. 2023 Jul;66(1):e45-e68. doi: 10.1016/j.jpainsymman.2023.02.315. Epub 2023 Feb 23.


Barrado-Martín Y, Hatter L, Moore KJ, Sampson EL, Rait G, Manthorpe J, Smith CH, Nair P, Davies N. Nutrition and hydration for people living with dementia near the end of life: A qualitative systematic review. J Adv Nurs. 2021 Feb;77(2):664-680. doi: 10.1111/jan.14654. Epub 2020 Nov 29.

Loofs TS, Haubrick K. End-of-Life Nutrition Considerations: Attitudes, Beliefs, and Outcomes. Am J Hosp Palliat Care. 2021 Aug;38(8):1028-1041. doi: 10.1177/1049909120960124. Epub 2020 Sep 18.

Shih YA, Wang C, Jin S, Feng W, Lu Q. Decision Making of Artificial Nutrition and Hydration for Cancer Patients at Terminal Stage-A Systematic Review of the Views From Patients, Families, and Healthcare Professionals. J Pain Symptom Manage. 2021 Apr 30:S0885-3924(21)00313-4. doi: 10.1016/j.jpainsymman.2021.04.013. Epub ahead of print.


Anantapong K, Davies N, Chan J, McInnerney D, Sampson EL. Mapping and understanding the decision-making process for providing nutrition and hydration to people living with dementia: a systematic review. BMC Geriatr. 2020 Dec 2;20(1):520. doi: 10.1186/s12877-020-01931-y.

Kingdon A, Spathis A, Brodrick R, Clarke G, Kuhn I, Barclay S. What is the impact of clinically assisted hydration in the last days of life? A systematic literature review and narrative synthesis. BMJ Support Palliat Care. 2020 Oct 12:bmjspcare-2020-002600. doi: 10.1136/bmjspcare-2020-002600. Epub ahead of print.

Palese A, Bressan V, Hayter M, Watson R. Enhancing independent eating among older adults with dementia: a scoping review of the state of the conceptual and research literature. BMC Nurs. 2020 Apr 21;19:32. doi: 10.1186/s12912-020-00425-x.

Soar N, Birns J, Sommerville P, Lang A, Archer S. Approaches to Eating and Drinking with Acknowledged Risk: A Systematic Review. Dysphagia. 2020 Apr 1. doi: 10.1007/s00455-020-10107-0. Epub ahead of print.


Anderson AK, Burke K, Bendle L, Koh M, McCulloch R, Breen M. Artificial nutrition and hydration for children and young people towards end of life: consensus guidelines across four specialist paediatric palliative care centres. BMJ Support Palliat Care. 2019 Oct 19. pii: bmjspcare-2019-001909. doi: 10.1136/bmjspcare-2019-001909. [Epub ahead of print]

Bozzetti F. The role of parenteral nutrition in patients with malignant bowel obstruction. Support Care Cancer. 2019 Dec;27(12):4393-4399. doi: 10.1007/s00520-019-04948-1. Epub 2019 Jul 17.

Pettifer A, Froggatt K, Hughes S. The experiences of family members witnessing the diminishing drinking of a dying relative: An adapted meta-narrative literature review. Palliat Med. 2019 Jul 1:269216319859728. doi: 10.1177/0269216319859728. [Epub ahead of print]


Forbat L, Kunicki N, Chapman M, Lovell C. How and why are subcutaneous fluids administered in an advanced illness population: a systematic review. J Clin Nurs. 2017 May;26(9-10):1204-1216. Epub 2017 Feb 14.


Chow R, Bruera E, Chiu L, Chow S, Chiu N, Lam H, McDonald R, DeAngelis C, Vuong S, Ganesh V, Chow E. Enteral and parenteral nutrition in cancer patients: a systematic review and meta-analysis. Ann Palliat Med. 2016 Jan;5(1):30-41.


Bruno VG. Hypodermoclysis: a literature review to assist in clinical practice. Einstein (Sao Paulo). 2015 Jan-Mar;13(1):122-8. Epub 2015 Mar 24.

Duems-Noriega, Oscar; Arino-Blasco, Sergio. Subcutaneous fluid and drug delivery: Safe, efficient and inexpensive. Reviews in Clinical Gerontology. Vol.25(2), May 2015, pp. 117-146. [No abstract available]

Gent MJ, Fradsham S, Whyte GM, Mayland CR. What influences attitudes towards clinically assisted hydration in the care of dying patients? A review of the literature. BMJ Support Palliat Care. 2015 Sep;5(3):223-31. Epub 2014 Mar 17.


Ivanović N, Büche D, Fringer A. Voluntary stopping of eating and drinking at the end of life - a 'systematic search and review' giving insight into an option of hastening death in capacitated adults at the end of life. BMC Palliat Care. 2014 Jan 8;13(1):1. doi: 10.1186/1472-684X-13-1.


Nwosu AC, Mayland CR, Mason SR, Khodabukus AF, Varro A, Ellershaw JE. Hydration in advanced cancer: can bioelectrical impedance analysis improve the evidence base? A systematic review of the literature. J Pain Symptom Manage. 2013 Sep;46(3):433-446.e6. Epub 2012 Nov 27.


Raijmakers NJ, van Zuylen L, Costantini M, Caraceni A, Clark J, Lundquist G, Voltz R, Ellershaw JE, van der Heide A; OPCARE9. Artificial nutrition and hydration in the last week of life in cancer patients. A systematic literature review of practices and effects. Ann Oncol. 2011 Jul;22(7):1478-86. Epub 2011 Jan 3.


Good P, Cavenagh J, Mather M, Ravenscroft P. Medically assisted hydration for palliative care patients. Cochrane Database Syst Rev. 2008 Apr 16;(2):CD006273. [Update 2023]


Bavin L. Artificial rehydration in the last days of life: is it beneficial? Int J Palliat Nurs. 2007 Sep;13(9):445-9


Viola RA, Wells GA, Peterson J. The effects of fluid status and fluid therapy on the dying: a systematic review. J Palliat Care. 1997 Winter;13(4):41-52.


Burge FI. Dehydration and provision of fluids in palliative care. What is the evidence? Can Fam Physician. 1996 Dec;42:2383-8.

Last updated 10 January 2024